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吸血类动物组织蛋白质组学研究进展 被引量：2

The Proteomics Progression of the Tissues from Bloodsuckers
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摘要 蛋白质组学技术作为重要的实验手段,已经成为研究人员筛选重大疾病的特异生物标志物和研究发病机理的新途径。总结了吸血类动物组织蛋白质组学研究的主要内容和研究方法,并简述了按蚊、水蛭、蜱类、血吸虫、七鳃鳗等吸血类动物的唾液腺、中肠、血液、排泄分泌物,以及口腔腺等组织的蛋白质组学研究进展,探讨了其在疾病防治和新药开发中的应用前景。 Recently,proteomics has been used as an important experiment technology for high throughput screening of specific biomarkers and pathogenesis of serious diseases.In the paper,the details and methods for proteomics research have been reviewed.In addition,the process on the proteomics research for the salivary glands,midguts,blood,excretions,and buccal glands from the bloodsuckers,such as anopheles,leeches,ticks,blood flukes,and lampreys has been also discussed,which can provide important information on the prevention of diseases and the development of novel drugs.
作者 张志林 肖蓉 勾萌 李庆伟
机构地区 辽宁师范大学生命科学学院 辽宁省生物技术与分子药物研发重点实验室
出处 《长江大学学报（自科版）（下旬）》 CAS 2014年第2期116-122,6,共7页 Journal of Yangtze University
基金 国家自然科学青年基金(31301880) 中国博士后科学基金面上资助项目(2013M541246) 高等学校博士学科点专项科研基金新教师类资助课题(20112136120002) 大连市科学技术基金(2011J21DW014) 辽宁省教育厅科学研究一般项目(L2011187)
关键词 蛋白质组学 吸血类动物 唾液腺 中肠 血液 排泄分泌物 proteomics bloodsuckers salivary glands midguts blood excretions
分类号 Q51 [生物学—生物化学]
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二级参考文献16

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同被引文献37

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  • 2李继红,崔茜,李小丹,伍杨,林平,刘锦红,熊茂来.旋毛虫培养液对人白血病细胞K562凋亡和坏死的影响[J].中国寄生虫学与寄生虫病杂志,2005,23(3):185-186. 被引量：2
  • 3胡新颖,刘欢,张楠,马长伟.白鲢骨骼肌丝氨酸蛋白酶抑制剂的提取、纯化及其特性[J].中国水产科学,2006,13(2):316-321. 被引量：5
  • 4王国英,马远方,刘广超,谷敬丽,张军,杜耀武.两种方法制备的旋毛虫ES抗原对小鼠免疫保护作用研究[J].免疫学杂志,2007,23(5):586-587. 被引量：6
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长江大学学报（自科版）（下旬）
2014年 第2期

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