多普勒检测颈动脉狭窄与血管性认知功能障碍关系的临床探讨

Clinical Study of the Relationship Between Carotid Artery Stenosis and Vascular Cognitive Impairment by Doppler Detection

目的研究颈动脉狭窄(carotid artery stenosis,CAS)与血管性认知功能障碍(vascular cognitive impairment,VCI)的相关性。方法随机选取47例确诊的VCI患者为实验组(VCI组),随机选取同期就诊47例非VCI患者作为对照,对两组人员行影像学检查,记录颈动脉狭窄发生率及内中膜厚度(Intimal-medial wall thickness,IMT),并进一步计算狭窄程度,结果进行相关统计学分析。结果 VCI组44例患者有不同程度的颈动脉狭窄,其中2例患者颈动脉完全闭塞,36例患者闭塞程度>50%。对照组;18例患者管腔清晰,内膜光滑,IMT<1 mm;颈动脉闭塞程度>50%的观察者仅12例。经秩和检验分析,VCI组与对照组相比差异有统计学意义,P<0.05。结论颈动脉狭窄可能对血管性认知功能障碍的形成有一定的影响。

Objective To study the correlation of carotid artery stenosis （ CAS ） and vascular cognitive impairment （ VCI ） . Method 47 patients diagnosed with VCI were randomly selected as the experimental group （VCI）, and other 47 cases of non-VCI patients were randomly selected from the same period as the control group.Imaging examinations were carried out on both groups, inci-dence of carotid stenosis and intimal-medial wall thickness （IMT） were recorded respectively.After calculating the degree of stenosis,＆amp;nbsp;the results were statistically analyzed.Results 44 patients in VCI group were with different degrees of carotid artery stenosis, inclu-ding 2 patients with 100%carotid artery occlusion, 36 patients with occlusive degree ＆gt;50%.In the control group, 18 patients were with clear and smooth intima, IMT 〈1 mm, only 12 cases with carotid artery occlusion degree 〉;50%.Through rank sum test analy-sis, the difference between VCI group and the control group was of statistical significance, P〈0.05.Conclusion Carotid artery steno-sis may have certain influence on the formation of vascular cognitive impairment .