左房容积指数对射血分数保留型心力衰竭的诊断价值分析

The diagnostic value of left atrial volume index for heart failure with preserved ejection fraction

目的:探讨左房容积指数(LAVI)对射血分数保留型心衰(HFPEF)的诊断价值。方法:入选2012年5月至2013年9月期间就诊于广东省人民医院的住院患者110例,包括病例组(HFPEF)77例和对照组(非HFPEF)33例。分别比较两组人群临床资料及超声心动图指标,对左房容积(LAV)、LAVI与各舒张功能指标之间行Pearson相关分析,应用ROC曲线对比LAV、LAVI在HFPEF中的诊断价值。结果:HFPEF组LAVI、LAV大于对照组,差异有统计学意义(P<0.05);LAV、LAVI与HFPEF具有良好的相关性;LAVI在诊断HFPEF中的ROC曲线下面积较LAV显著增大(0.832 vs.0.799,P<0.05);以30 mL/m2作为截点,其特异度为64.9%,敏感度为84.8%。结论:LAVI对HFPEF具有一定的诊断价值。

Objective To explore the value of left atrium volume index （LAVI） in the diagnosis of heart failure with preserved ejection fraction （HFPEF）. Methods Seventy-seven patients with HFPEF and 33 patients without HFPEF who had been treated from May 2012 to September 2013 in Guangdong General Hospital were en- rolled. The clinical data and a series of ultrasound parameters were collected and analysed. The relationship between LAVI, LAV, and other indexes of diastolic function was determined by Pearson correlation analysis. The value of LAVI and LAV for diagnosing HFPEF was compared by the ROC curve. Results LAVI and LAV of were signifi- cantly greater in HFPEF group than in non-HFPEF group. LAV and LAVI were significantly associated wtih HEPEF. The area under the ROC curve （AUC） of LAVI increased significantly as compared with the AUC of LAV （0.832vs. 0.799, P〈0.05）. With a cut-off value of 30 mL/m2, the specificity and sensitivity for diagnosing HEPEF were 64.9% and 84.8%, respectively. Conclusions LAVI may be valuable in the diagnosis of HFPEF.