乳腺可视化触诊成像系统鉴别诊断乳腺良恶性病变:与临床触诊、X线及超声对照

Palpation imaging system in differentiating benign and malignant breast lesions:Compared with physical examination,mammography and ultrasonography

目的探讨乳腺可视化触诊成像系统对乳腺病灶良恶性病变的鉴别诊断价值。方法对169例乳腺病变患者(共195个病灶)行触诊成像、临床触诊和X线,对其中151例行超声检查。比较以上4种方法鉴别乳腺良恶性病变的敏感度、特异度,评估各方法对不同腺体类型乳腺病灶的诊断价值。结果触诊成像对良恶性病灶的诊断敏感度为82.40%,特异度为80.00%,敏感度高于临床触诊(60/125,48.00%,P<0.001)但低于X线(117/125,93.60%,P=0.003)及超声(105/110,95.45%,P<0.001),特异度高于X线(39/70,55.71%,P=0.002)及超声(38/61,62.29%,P=0.023)。对于不同腺体类型的乳腺,触诊成像鉴别良恶性病灶的敏感度和特异度变化不大。结论触诊成像对于鉴别乳腺良恶性病灶具有较高的应用价值,有望成为现有乳腺检查技术的补充。

Objective To evaluate the efficacy of palpation imaging （PI） in differentiation of benign and malignant breast lesions. Methods A total of 169 patients （195 breast lesions confirmed by pathology） underwent PI, physical examination and mammography, among them 151 people underwent ultrasonography. The efficacies of 4 examinations in differentiating benign and malignant lesions were compared. Results The sensitivity of PI for differentiating benign and malignant lesions （82.40%） was higher than that of physical examination （60/125, 48.00%, P〈0. 001）, but lower than that of mammog- raphy （117/125, 93.60%, P=0.003） and ultrasound （105/110, 95.45%, P〈0.001）. The specificity of PI （80.00%） was high than that of mammography （39/70, 55.71%, P=0. 002） and ultrasound （38/61, 62.29%, P=0. 023）. For pa- tients with different type of breast composition on mammography, the sensitivity and specificity of PI were stable. Conclu- sion PI has capability to distinguish benign and malignant breast lesions, and may become an important supplement of ul- trasound, mammography in diagnosis of breast diseases.