老年性房间隔缺损介入封堵治疗临床观察

Clinical effect of transcatheter closure in elderly patients with atrial septal defect

目的探讨介入封堵治疗对老年性房间隔缺损的临床疗效。方法选取我院于2008年1月-2012年6月收治的老年性房间隔缺损患者27例,对其进行介入封堵治疗,观察其临床治疗效果。结果 27例患者均封堵成功,成功率为100%,术后并发症发生率为3.7%(1/27),介入封堵治疗后,在肺动脉压力、右心室内径以及三尖瓣的反流面积上,与介入治疗前相比差异明显,P<0.05,差异有统计学意义。结论介入封堵治疗老年性房间隔缺损患者,成功率高,创伤小,疗效显著,且手术安全可靠,值得临床推广与应用。

Objective To investigate the clinical effect of transcatheter closure in elderly patients with atrial septal defect. Methods Twenty-seven elderly patients with atrial septal defect admitted to our hospital from January 2008 to June 2012 were included in the study. Transcatheter closure of atrial septal defect was performed. The treatment outcomes were evaluated. Results Transcatheter closure was successfully completed in all patients, with a success rate of 100%. The incidence of postoperative complications was 3.7% （1/27）. After transcatheter closure, these patients showed significant improvements in pulmonary artery pressure, right ventricular internal dimension, and tricuspid regurgitant orifice area （P 〈0.05）. Conclusion Transcatheter closure has the advantages of high success rate, little trauma, good efficacy, and high safety in elderly patients with atrial septal defect, so it holds promise for clinical application.