支气管哮喘急性发作患者的用药方案分析

Analysis on Drug Use Regime for Acute Bronchial Asthma Patients

目的:探讨支气管哮喘急性发作的临床合理用药。方法:回顾性分析符合纳入标准的165例支气管哮喘急性发作患者的治疗使用药物类别、药品名称、给药途径、抗菌药物应用、联合用药、不良反应及用药合理性等。结果:使用糖皮质激素患者145例,占87.9%,使用速效β2受体激动剂患者165例,占100%;合并感染者58例均应用抗菌药物,未合并感染征象者107例中46例应用抗菌药物,占42.9%;糖皮质激素采用雾化吸入78例,占47.3%,β2受体激动剂和M受体阻断剂均采用吸入给药;所有病例均联合用药,其中4种药物联合使用率最高,占32.7%;出现药物不良反应患者16例,占9.7%;不合理用药13例,占总病例的7.9%。结论:我院绝大多数哮喘患者能接受规范化的药物治疗,针对存在的不足,还应鼓励临床药师在临床实践中实施全程药学监护,促进合理用药。

Objective： discussion and study on proper clinical drug use for acute bronchial asthma patients. Methods： retrospective analysis on the up -to -standard 165 cases of acute bronchial asthma patients in terms of drug classification, drug name, drug delivery route, antibacterial drug application, drug combination, untoward effect and proper drug use etc. Results： 145 cases of glucocorticoid users taking up 87.9% in 13 - rated quick - acting; 165 cases of receptor stimulant users taking up 100% ; 58 cases of antibacterial drug applied concurrent in- fected patients and antibacterial drug applied for 46 out of 107 cases of non - concurrent infected patients, accounting for 42. 9% ; aerosol glucocorticoid intake applied for 78 cases taking up 47.3%, 13 ; Receptor stimulant and receptor blocker both are applied as aerosol intake ; 4 drugs are among the top ranking in join use taking up 32. 7% ; 16 patients have untoward effect taking up 9.7% ; 13 cases of improper drug use taking up 7.9% of the total cases; Conclusions： most asthma sufferers are able to bear regulated drug therapy, clinicians shall be encouraged to carry pharmaceutical care throughout the whole course for proper drug use in clinical practices.