过渡金属催化的(杂)芳烃C-H/C-H交叉氧化偶联反应进展

Recent development of transition metal-catalyzed oxidative C-H/C-H cross-coupling of two (hetero)arenes

过渡金属催化的(杂)芳烃与(杂)芳烃之间的氧化C-H/C-H交叉偶联反应已成为构筑联(杂)芳基骨架的重要策略。近年来,许多令人瞩目的研究成果不断涌现,其反应类型主要可以分为未活化芳烃间的交叉脱氢偶联反应、未活化芳烃与杂芳烃的交叉脱氢偶联反应以及杂芳烃与杂芳烃之间的交叉脱氢偶联反应三种类型。本文主要综述了这三类反应的最新研究进展,介绍了各类反应的特点、优势及在合成中的应用。

Transition metal catalyzed oxidative C H/C--H cros-coupling between two （hetero）arenes is one of the most attractive approaches to bi（hetero）aryls. In recent years, a number of successful examples of the dehydrogenative coupling between two simple arenes, between a heteroarene and an arene, and between two heteroarenes have been reported. This review focuses specifically on the recent development and detailed analysis on the versatility and practicality of these transformations of cros-dehydrogenative coupling between two （hetero）arenes.