钆喷酸葡胺在颅脑核磁共振增强扫描中剂量的选择

Gd- DTPA Dose Selection in Enhanced Brain MRI Scan

目的探讨颅脑核磁共振(MRI)增强扫描造影剂最适剂量。方法选取90例需要颅脑核磁共振增强患者,根据造影剂剂量分组:A组30例,按体重1次0.1 mL/kg(或0.05 mmoL/kg);B组30例,按体重1次0.2 mL/kg(或0.1 mmoL/kg);C组30例:按体重1次0.4 mL/kg(或0.2 mmoL/kg)。结果 A组强化效果不能达到诊断要求,B组可以达到诊断要求,剂量较小,C组达到诊断要求,剂量大。结论按体重1次0.2 mL/kg(或0.1 mmoL/kg)注射造影剂是颅脑MRI增强扫描最佳剂量。

Objective To investigate the optimal dose of MRI in enhanced scanning contrast agent. Methods Selecting 90 cases with enhanced brain MRI. According to dose, cases were divided into： 30 patients in group A with O. 1 mL/kg （or 0.05 mmol/kg） once according to body weight, 30 cases in group B with O 2 mL/kg （ or of 0. 1 mmol/kg） by weight, 30 patients in group C with O. 4 mL/kg （ or the 0. 2 mmol/kg） by weight. Results Strengthening effect of group A can not meet diagnostic needs, group B can reach the diagnostic requirements with a smaller dose, and group C meet the diagnostic requirements in large doses. Conclusion 0. 2 mL/kg （or of O. 1 mmol/kg） injection once of contrast medium is the most appropriate brain enhanced MRI optimal dose by weight.