期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

鼻腔呼出气一氧化氮无创检测及其临床意义 被引量：10

原文传递
导出
摘要 一氧化氮（nitric oxide,NO）是一种极不稳定的生物自由基,其生成依赖一氧化氮合成酶（nitric oxide synthase,NOS）.1978年Murad等[1]发现,NO可引起血管舒张.1980年Furchgott和Zawadzki[2]发现,血管内皮细胞产生一种未知的物质,可导致平滑肌松弛,这种物质就是NO,但当时被称为“内皮源性舒张因子”.1998年上述三位科学家因发现NO在心血管系统中作为一种信号分子被授予诺贝尔生理学和医学奖.1991年Gustafsson等[3]首次发现NO存在于人的呼出气中.1992年NO被Science杂志命名为“明星分子”.
作者 白银 尤少华 张静 王洪田
机构地区 解放军总医院耳鼻咽喉头颈外科
出处 《中华耳鼻咽喉头颈外科杂志》 CAS CSCD 北大核心 2014年第4期341-346,共6页 Chinese Journal of Otorhinolaryngology Head and Neck Surgery
基金 解放军总医院临床科研扶持基金（2012FC-TSYS-2010）
关键词 呼出气一氧化氮 临床意义 无创检测 内皮源性舒张因子 一氧化氮合成酶 OXIDE 鼻腔 血管内皮细胞
分类号 R765.04 [医药卫生—耳鼻咽喉科]
  • 相关文献

参考文献64

  • 1Murad F, Mittal CK, Arnold WP, et al. Guanylate cyclase : activation by azide, nitro compounds, nitric oxide, and hydroxyl radical and inhibition by hemoglobin and myoglobin [ J ]. Adv Cyclic Nucleotide Res, 1978,9 : 145-158.
  • 2Furchgott RF, Zawadzki JV. The obligatory role of endothelial ceils in the relaxation of arterial smooth muscle by acetylcholine [ J ]. Nature, 1980 ,288 (5789) :373-376.
  • 3Gustafsson LE, Leone AM, Persson MG, et al. Endogenous nitric oxide is present in the exhaled air of rabbits, guinea pigs and humans [ J]. Biochem Biophys Res Commun, 1991 , 181 (2) :852- 857.
  • 4Alving K, Weitzberg E, Lundberg JM. Increased amount of nitric oxide in exhaled air of asthmatics [ J ]. Eur Respir J, 1993 ,6 ( 9 ) : 1368-1370.
  • 5Lundberg JO, Weitzberg E, Nordva11 SL, et al. Primarily nasal origin of exhaled nitric oxide and absence in Kartagener' s syndrome [ J ]. Eur Respir J, 1994 ,7 ( 8 ) : 1501-1504.
  • 6Weitzberg E, Lundberg JO. Humming greatly increases nasal nitric oxide[J]. Am J Respir Crit Care Med, 2002,166(2) :144- 145.
  • 7Hood CM, Schroter RC, Doorly DJ, et al. Computational modeling of flow and gas exchange in models of the human maxillary sinus [ J ]. J Appl Physiol, 2009,107 ( 4 ) : 1195-1203.
  • 8Maniscalco M, Lundberg JQ. Nasal nitric oxide [ J ]. Eur Respir Mon, 2010, 49: 71-81.
  • 9Marthin JK, Nielsen KG. Hand-held tidal breathing nasal nitric oxide measurement-a promising targeted case-finding tool for the diagnosis of primary ciliary dyskinesia [ J]. PLoS One, 2013,8 (2) : e57262.
  • 10张罗,罗雪瑞,刘承耀,赵岩,韩德民.健康成人口鼻呼出气一氧化氮含量测定及其影响因素分析[J].中华耳鼻咽喉头颈外科杂志,2009,44(4):302-306. 被引量：19

二级参考文献68

  • 1American Thoracic Society, European respiratory Society. ATS/ ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide. Am J Respir Crit Care Med, 2005, 171 : 912-930.
  • 2Kharitonov S, Alving K, Barnes PJ. Exhaled and nasal nitric oxide measurements: recommendations. The European Respiratory Society Task Force. Eur Respir J,1997, 10: 1683-1693.
  • 3Kharitonov SA, Walker L, Barnes PJ. Repeatability of standardised nasal nitric oxide measurements in healthy and asthmatic adults and children. Respir Med, 2005, 99 : 1105-1114.
  • 4Recommendations for standardized procedures for the on-line and off-line measurement of standardized lower respiratory nitric oxide and nasal nitric oxide in adults and children-1999. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999. Am J Respir Crit Care Med, 1999, 160: 2104-2117.
  • 5Struben VM, Wieringa MH, Mantingh C J, et al. Nasal NO: normal values in children age 6 through to 17 years. Eur Respir J, 2005, 26: 453-457.
  • 6Girand GD, Nejadnik B, Kimberly B, et al. Physical characteristics and gas composition of nasal air affect nasal nitric oxide release. Respir Physiol, 1995,114 : 285-296.
  • 7Franklin PJ, Stick SM, Turner SW, et al. Measuring exhaled nitric oxide levels in adults: the importance of atopy and airway responsiveness. Chest,2004,126: 1540-1545.
  • 8Tsang KW, Ip SK, Tipoe GL, et al. Exhaled nitric oxide: the effects of age, gender and body size. Lung,2001,179 : 83-91.
  • 9Palm PJ, Graf P, Lundberg JO, et al. Characterization of exhaled nitric oxide : introducing a new reproducible method for nasal nitric oxide measurements. Eur Respir J, 2000, 16 : 236-241.
  • 10Zetterquist W, Pedroletti C, Lundberg JO, et al. Salivary contribution to exhaled nitric oxide. Eur Respir J, 1999, 13: 327 -333.

共引文献5081

同被引文献60

引证文献10

二级引证文献22

中华耳鼻咽喉头颈外科杂志
2014年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部