乙氧硬化醇和聚桂醇治疗食管静脉曲张破裂出血疗效及并发症比较

Ethyl alcohol lauromacrogol hardening treatment of esophageal variceal bleeding compared the efficacy and complications

目的:对比观察内镜下注射硬化剂乙氧硬化醇与聚桂醇治疗食管静脉曲张破裂出血的疗效及并发症。方法:收集肝硬化合并食管静脉曲张破裂出血的患者227例均采用内镜下食管曲张静脉硬化剂注射治疗。根据硬化剂种类不同分成两组:A组120例次给予乙氧硬化醇注射治疗,B组107例次给予聚桂醇注射治疗。观察两组患者治疗后72h止血率及并发症如发热等的发生率。结果:两种硬化剂治疗后72h止血率相当,无明显差异,但是B组术后发热的发生率较A组升高,且有统计学意义,其余并发症的发生率两组无显著性差异。结论:内镜下采用乙氧硬化醇和聚桂醇治疗食管静脉曲张破裂出血,止血率相当,除发热外其它并发症发生率也无明显差异,聚桂醇是一种安全有效的硬化剂。

Objective：To compare the efficacy and complications of the bleeding of esophageal varices which coursed by injecting sclerotherapy aethoxysklerol and lauromacrogol under endoscopic .Methods ：Collection of liver cirrhosis with esophageal variceal bleeding in 227 patients were treated by endoscopic variceal sclerotherapy .Ac-cording to the different types of hardener into two groups ：Group A ,120 cases given aethoxysklerol injection ;Group B ,107 cases given lauromacrogol injection .We observed 72 hours bleeding rate and complications such as fever and so on .Results ：The result suggested that there were no significant difference in72 hours bleeding rate ,but the inci-dence of fever in Group B was more than the other one and with statistical significance .The incidence of the rest of complications was no significant difference .Conclusion：Endoscopy with aethoxysklerol and lauromacrogol in treat-ment of esophageal variceal bleeding ,bleeding rate ,other complications except fever incidence has no obvious differ-ence ,lauromacrogol is a safe and effective curing agent .