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梅毒血清学筛选试验CMIA和TRUST的临床评价

Clinical evaluation of syphilis antibody screening by CMIA and TRUST
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摘要 目的:评价化学发光微粒子免疫分析法(CMIA)和甲苯胺红不加热血清学试验(TRUST)在梅毒血清学筛选试验中的应用价值。方法:分别用CMIA方法和TRUST方法检测住院患者的血清标本共1 921例,并比较梅毒检测结果。结果:CMIA方法检出163例阳性,阳性率8.49%;TRUST方法检出131例阳性,阳性率6.82%,两者差异有统计学意义(P<0.05)。结论:CMIA方法较TRUST可以很大提高梅毒抗体检测的工作效率,其有漏检率低、操作简单方便、检测周期短、能批量检测等优点,可推荐为临床检验科梅毒血清学筛选试验的方法。 Objective:To evaluate the application value of CMIA and TRUST in screening test of syphilis anti- bodies. Method: A total of 1921 serum specimens were tested for syphilis by CIMA and TRUST. Result: One hun- dred and sixty-three out of 1921 serum specimens were tested positive by CMIA method,with the positive rate of 8.49%;131 out of 1921 serum specimens were tested positive by TRUST method,with the positive rate of 6. 82 %. Two methods were significant differences (P 〈0. 05). Conclusion: By comparing the two methods, CMIA method could greatly improve the working efficiency of clinical laboratory syphilis antibody detection, which has some advantages such as low miss rate, simple and convenient operation, short detection period and batch detec- tion,and could he recommended as a method for clinical laboratory syphilis serology screening test.
作者 易娟 韩卫全
出处 《临床血液学杂志》 CAS 2014年第2期126-127,共2页 Journal of Clinical Hematology
关键词 梅毒 微粒子化学发光法 甲苯胺红不加热血清学试验 syphilis chemiluminescence microparticle immunoassay toluidine red unheated serum test
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