圆滑番荔枝的化学成分研究

Study on the Chemical Constiuents of Annona glabra

目的 :从番荔枝科植物圆滑番荔枝 ( Annona glabra Linn.)树皮提取分离活性成分。方法 :95%乙醇提取、溶剂萃取、硅胶柱层析、重结晶等。结果 :分离到 6个化合物 ,其中 5个为贝壳杉烷型二萜 ,1个生物碱。5个二萜 、 、 、 、 分别为 ( -) -kaur-1 6-en-1 9-oic acid、1 6α-hydro-1 9-acetoxy-ent-kauran-1 7-oic acid、( -) -kau-ran-1 9-al-1 7-oic acid、ent-1 9-carbomethoxykauran-1 7-oic acid、1 9-hydroxy-1 6α-( -) -kauran-1 7-oicacid,生物碱为oxoglaucine。结论 :萜 ent-1 9-carbomethoxykauran-1 7-oic acid、萜 1 9-hydroxy-1 6α-( -) -kauran-1 7-oic acid和生物碱 oxoglaucine为首次从该植物中分得。

AIM:Bio active constituents were expected to be obtained from \%Annona glabra\% Linn. METHODS: It is extracted with 95% alcohol, distributed by different solvents, isolated via column chromatography on silica gel and purified by crystallization et al. RESULTS: Six compounds were isolated from \%Annona glabra\% Linn. Among them, five compounds were kaurane diterpenoids and one compound was alkaloid. On the basis of the preperties and spectral analysis, their structures were identified as terpeneⅠ( ) kaur 16 en 19 oic acid、terpeneⅡ16α hydro 19 acetoxy ent kauran 17 oic acid、terpeneⅢ( ) kauran 19 al 17 oic acid、terpene Ⅳent 19 carbomethoxykauran 17 oic acid、terpeneⅤ 19 hydroxy 16α ( ) kauran 17 oic acid and alkaloid oxoglaucine. CONCLUSION: Among them, ent 19 carbomethoxykauran 17 oic acid、19 hydroxy 16α ( ) kauran 17 oic acid and oxoglaucine were isolated from this plant for the first time.