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蛋白激酶C在某些疾病中的作用 被引量:3

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摘要 蛋白激酶C(PKC)是细胞信号转导的主要组成部分 ,对细胞的生长分化、血管平滑肌收缩和死亡等的信号转导均起重要作用。已发现PKC对机体多种疾病的发生和发展具有重要意义 ,研究PKC在这些疾病中的作用不仅可以进一步了解其发生机制 ,而且可为这些疾病的诊断和治疗提供新的途径。
出处 《国外医学(生理病理科学与临床分册)》 2001年第1期45-47,共3页 Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
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  • 1[1]Mellor H, Parker PJ. Biochem J, 1998,332(1):281-292.
  • 2[2]Murray NR, Fields AP. J Biol Chem, 1997,272(44):27521-27524.
  • 3[3]Fleming I, MacKenzie SJ, Vernon RG, et al. Biochem J, 1998,333(2): 719-727.
  • 4[4]Frey MR, Saxon ML, Zhao X, et al . J Biol Chem, 1997,272(14):9424-9435.
  • 5[5]Harrington EO, Loffler H, Nelson PR, et al . J Biol Chem, 1997,272( 11 ): 7390-7397.
  • 6[6]Zhu DM, Fang WH, Narla RK, et al. Clin Cancer Rev, 1999,5(2):355 -360.
  • 7[7]Mayne GC, Murray AW. J Biol Chem, 1998,,273(37):24115.
  • 8[8]Jamieson L, Carpenter L, Biden TJ, et al . J Biol Chem, 1999,274(7): 3927-3930.
  • 9[9]Throckmorton DC, Packer CS, Brophy. J Surg Res, 1998,78(1):48-53.
  • 10[10]Wilkinson SE, NixonJS. Cell Mol Life Sci, 1998,54(5):1122-1144.

同被引文献25

  • 1王旭开.蛋白激酶C在血管平滑肌细胞中的调控作用及其检测[J].国外医学(生理病理科学与临床分册),1994,14(1):45-48. 被引量:1
  • 2Zhu DL, Herembert T, Caruelle D, et al. Signaling mechanisms of basic fibroblast growth factor in arterial cells from genetically hypertensive rat[J]. Am J Hypertens, 1994,7:351 - 356.
  • 3Shi Y, O'Brien JE Jr, Fard A, et al. Transforming growth factor- beta 1 expression and myofibroblast formation during arterial repair[ J ]. Arterioscler Thromb vasc biol, 1996,16(10) : 1298- 1305.
  • 4Evans RA, Tian YC, Steadman R, et al. TGF- betal - mediated fibroblast - myofibroblast terminal differentiation - the role of Smad proteins[J]. Exp Cell Res, 2003,282(2):90- 100.
  • 5Serini G, Gabbiani G. Mechanisms of myofibroblast activity and phenotypic modulation[J ]. Exp Cell Res, 1999,250 : 273 - 283.
  • 6Pratschke J,Wilhelm MJ,Kusaka M,et al.A model of gradual onset brain death for transplant-associated studies in rats[J].Transplantation,2000,69(3):427
  • 7Lanza RP,Cooper DK,Novitzky D,et al.Survival after cardiac transplantation[J].S Afr Med J,1983,64(26):1007
  • 8Blaine EM,Tallman RD Jr,Frolicher D,et al.Vasopressin supplementation in a porcine model of brain-dead potential organ donors[J].Transplantation,1984,38(5):459
  • 9Wang QJ,Acs P,Goodnight J,et al.The catalytic domain of PKC-ε,inreciprocal PKC-δ and-ε chimeras,is responsible for conferring tumorgenicity to NIH3T3 cells,whereas both regulatory and catalyticdomins of PKC-ε contribute to in vitro transformation[J].Oncogene,1998,16(1):53
  • 10Togashi H,Hirshrnan CA,Emala CW.Qualitative immunoblot analysis of PKC isoforms expressed in airway smooth muscle[J].Am J Physiol,1997,272(4 Pt 1):L603

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