自组装DNA计算仿真软件及其应用综述

Review of simulation computation of DNA self-assembly system and the related application research

综述了用于自组装DNA计算仿真软件caDNAno工具、Visual DSD工具和NUPACK工具的发展现状,并以基于caDNAno软件平台设计郑州轻工业学院校徽二维DNA自组装结构模型、采用Visual DSD工具设计用于素数判断的DNA分子计算模型并进行相关仿真实验为例,对自组装DNA计算仿真软件的应用进行可行性论证与探讨,指出:随着自组装DNA计算研究的深入,应用新的生物技术开发更为高效实用的软件将是未来的研究方向.

Some existing DNA computing sofiwares, such as caDNAno tools, Visual DSD tools and NU- PACK tools,were reviewed. Based^n the caDNAno and Visual DSD, two DNA self-assembly models were described,which are respectively correspontling to Zhengzhou University of Light Industry badge and the prime number judging. After that, the application and feasibility of related＂ softwares was discussed. And then, it was pionted that software platforms design was an important issue in the research of DNA self- assembly comoutation.