卡前列素氨丁三醇在产后出血中的应用

Treatment of Atonic Postpartum Hemorrhage with Carboprost Tromethamine

目的评价卡前列素氨丁三醇(欣母沛)用于治疗子宫收缩乏力所致产后出血的疗效,探讨卡前列素使用的适应症和最佳使用时间。方法对使用卡前列素治疗的87例产后出血患者进行回顾性分析,并将未用卡前列素的产后出血病例87例作为对照。结果卡前列素组87名患者中,69例疗效显著,14例有效,总有效率达95.4%,无效4例,2例行子宫切除术。结论卡前列素治疗宫缩乏力性产后出血疗效确切,并具有使用方便、安全、显效快的特点,但注意应在出血的早期应用。

Objective To observe curative effect of carboprost tromethamine （Hemabate） for controlling atonic postpar- tum hemorrhage. Methods A retrospective anaiysis was undertaken on 87cases of atonic postpartum hemorrhage which were trea- ted with Hemabate ,and 87 cases which didn＇ t use Hemabate were regarded as controlled group. Results The hemorrhage was successfully controlled immediately after administration of Hemabate in 69 of 87cases. The total effective rate was 96. 5%, four ca- ses failed and two were performed hysterectomy. Conclusion Hemabate appeared very effective for treatment of severe atonic post- partum hemorrhage. It also has the characters of convenience, safety, quick and high performance. It should be used actively at the early stage of postpartum hemorrhage.