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孟鲁司特联合环索奈德治疗支气管哮喘的临床疗效研究 被引量:5

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摘要 目的探讨孟鲁司特联合环索奈德治疗支气管哮喘(哮喘)的临床疗效。方法选取2013年3—9月我院收治的哮喘患者200例,将其随机分为试验组和对照组,各100例。对照组采用环索奈德治疗,试验组在对照组基础上采用孟鲁司特治疗,疗程均为8周。观察两组临床疗效、肺功能指标变化〔第1秒用力呼气末容积(FEV1)、呼气峰值流速(PEFR)〕及不良反应发生情况。结果试验组治疗总有效率为91.0%(91/100),高于对照组的78.0%(78/100)(χ2=11.572,P=0.003)。治疗前两组FEV1、PEFR比较,差异无统计学意义(P>0.05);治疗4、8周后试验组FEV1和PEFR均高于对照组(P<0.05)。两组均未出现明显不良反应。结论孟鲁司特联合环索奈德治疗哮喘疗效确切,无明显不良反应,值得临床推广应用。
出处 《实用心脑肺血管病杂志》 2014年第4期58-59,共2页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
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