经鼻双相正压通气治疗新生儿呼吸暂停疗效观察被引量：2

Observation of therapeutic effect of nasal biphasic positive pressure ventilation in the treatment of neonatal apnea

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摘要目的观察经鼻双相正压通气(N-BiPAP)治疗新生儿呼吸暂停的疗效。方法将我院新生儿监护病房诊断为呼吸暂停的患儿共58例,随机分为两组,每组29例。分别采用N-BiPAP和氨茶碱治疗,比较两组疗效。结果 N-BiPAP治疗后12 h及24 h,N-BiPAP组PaO2高于对照组,PaCO2低于对照组,差异均有统计学意义。结论对大多数新生儿呼吸暂停患儿采用N-BiPAP治疗能取得很好的临床疗效。 Objective To evaluate the efficacy of nasal biphasic positive pressure ventilation （N-BiPAP） in the treatment of neonatal apnea.Methods 58 newborns were randomly divided into two groups,29 cases in each group.The observation group was treated with N-BiPAP ventilation,and the control group was treated with aminophylline.Their efficacy of the two groups was compared.Results The level of PaO2 12h and 24h after the treatment was higher in the observation group than in the control group,while the level of PaCO2 was lower in the observation group than in the control group.Conclusion For the majority of neonatal apnea,N-BiPAP therapy can achieve good clinical efficacy.

作者凌厉包志丹

机构地区东南大学附属江阴市人民医院

出处《临床肺科杂志》 2014年第5期820-822,共3页 Journal of Clinical Pulmonary Medicine

关键词经鼻双相正压通气新生儿呼吸暂停 nasal biphasic positive pressure （N-BiPAP） neonate apnea

分类号 R722.1 [医药卫生—儿科]

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1金汉珍黄德珉官希吉.实用新生儿学[M].北京:人民卫生出版社,2000:178.
2柳国胜.新生儿呼吸暂停[J].实用儿科临床杂志,2007,22(2):89-92. 被引量：70
3Finer NN, Higgins R, Kattwinkel Jet al. Summary proceedings from the apnea of prematurity group [ J ]. Pediatrics, 2006, 117 (3Pt2) :$47 -51.
4Poblano A, Marquez A, Hemandez G. Apnea in infants [ J ]. Indian J Pediatr,2006,73(12) :1085 -1088.
5Henderson-Smart DJ. The effect of gestational age on the incidenee and duration of recurrent apnea in newborn babies[ J]. Aust paed- iatr, 1981,17 (4) :273 - 276.
6Moriette G, Lescure S, EI Ayoubi M,et al. Apnea of Prematurity : what's new? [J] Arch Pediatr,2010,17(2) :186 -190.
7赵婧,母得志.早产儿呼吸暂停诊治进展[J].临床儿科杂志,2012,30(3):291-294. 被引量：58
8Davis PG,, Morley C J, Owen LS. Non-invasive respiratory Support of preterm neonates with respiratory distress: continuous positive airway pressure and nasal intermittent positive pressure venti!.ation [ J ]. Semin Fetal Neonatal Med, 2009,14 ( 1 ) : 14 - 20.
9俞森洋.现代机械通气的理论和实践[M].北京:中国协和医科大学出版社,2009:379-381.
10Chang HY, Claure N, Dugard C, et al. Effects of synchronization during nasal ventilation in clinically stable preterm infants [ J ]. Pediatr Res, 2011,69 ( 1 ) : 84 - 89.

二级参考文献49

1张秀珍.早产儿原发性呼吸暂停40例[J].实用儿科临床杂志,2002,17(S1). 被引量：42
2李凤启.纳洛酮联合东莨菪碱治疗早产儿呼吸暂停48例[J].实用儿科临床杂志,2005,20(4):363-364. 被引量：16
3Schmidt B,Roberts RS,Davis P,et al.Long-term effects of caffeine therapy for apnea of prematurity[J].N Engl J Med,2007,357(19):1893-1902.
4Gray PH,Flenady VJ,Charles BG,et al.Caffeine citrate for very preterm infants:effects on development,temperament and behaviour[J].J Paediatr Child Health,2011,47(4):167-172.
5Mueni E,Opiyo N,English M.Caffeine for the management of apnea in preterm infants[J].Int Health,2009,1(2):190-195.
6Gaugler C,Marlier L,Messer J.Sensory stimulations for the treatment of idiopathic apneas of prematurity[J].Arch Pediatr,2007,14(5):485-489.
7Bloch-Salisbury E,Indic P,Bednarek F,et al.Stabilizing imma-ture breathing patterns of preterm infants using stochastic mechanosensory stimulation[JJ.J Appl Physiol,2009,107(4):1017-1027.
8Marlier L,Gaugler C,Messer J.Olfactory-stimulation prevents apnea in premature newborns[J].Pediatrics,2005,115(1):83-88.
9Al-Saif S,ATvaro R,Manfreda i.et al.A randomized controlled trial of theophylline versus CO2 inhalation for treating apnea of prematurity[J].J Pediatr,2008,153(4):513-518.
10Malcolm WF,Smith PB,Means S,et al.Transpyloric tube feeding in very low birthweight infants with suspected gastroeso-phageal reflux; impact on apnea and bradycardia[J].J Perinatol,2009,29(5):372-375.