肺泡蛋白沉积症的影像学诊断与临床分析

Imaging diagnosis and clinical analysis of pulmonary alveolar proteinosis

目的通过肺泡蛋白沉积症(PAP)的X线、CT影像学表现与临床特点,提高对本病的认识。方法回顾分析7例经病理证实的肺泡蛋白沉积症患者的X线、CT影像学及临床表现。结果影像学表现多样化,主要为地图样表现、碎石路样表现、肺实变表现(支气管充气征)、肺水肿样表现及肺间质纤维化样表现等,肺部阴影明显而且相对稳定,但是临床症状较轻。典型的影像学表现与临床症状常不相称是PAP的特点。结论肺泡蛋白沉积症影像学表现具有一定的特征性,结合临床症状,基本能作出正确诊断,确诊有赖病理。

Objective To investigate the X-ray,CT imaging features and clinical characteristics of pulmonary alveolar proteinosis.Methods X-ray,CT imaging and clinical findings of 7 patients with pathology confirmed pulmonary alveolar proteinosis were retrospectively reviewed.Results The imaging features of PAP were diversified,such as map-like,gravel,lobar or segmental consolidation,pulmonary edema,and interstitial fibrosis.Lung shadows were obvious and relatively stable,but with light clinical manifestation.The main feature of PAP was the typical imaging findings were not matched with the clinical symptoms.Conclusion The imaging features of PAP show a certain mark,and the accurate diagnosis of PAP can be made by combining with clinical symptoms.