摘要
目的 :探讨原发性卵巢平滑肌肉瘤的临床特点及诊断、治疗方法。方法 :对 2例原发性卵巢平滑肌肉瘤进行临床报告及分析。结果 :原发性卵巢平滑肌肉瘤可发生在任何年龄 ,临床表现不典型。诊断主要依靠病理 ,核分裂数为主要依据 ,同时结合免疫组化 Desmin(- ) ,Vimentin(+ )诊断。结论 :原发性卵巢平滑肌肉瘤恶性度高 ,预后差 ,治疗需以手术为主 。
Objectives:To describe the clinical characteristics and the role of diagnosis and treatment in Primary Ovarian Leiomyosarcoma(POLMS).Method:Two patients with POLMS were presented focusing on th clinical manifestations and outcome of the treatment.Results:POLMS may occur at any ages and clinical features were not typical.Diagnosis was made by pathology and main numerous atypical mitoses,cells showed severe hyperchromatism,and mitoses ranged up to 20 per 10 high power fields in leiomyosarcoma.Immunohistochemical staining of the sarcoma was negative for Desmin and strongly positive throughout for Vimentin.Conclusions:POLMS is a high degree malignant tumor and have a dismal prognosis.Surgical management is recommended predominantly and with suitable adjuvant chemotherapy and radiation,particularly surgical excision is main point.
出处
《实用妇产科杂志》
CAS
CSCD
北大核心
2001年第1期40-41,共2页
Journal of Practical Obstetrics and Gynecology