乳腺癌患者术后感染临床分析

Clinical analysis of infection in breast cancer patients after therapy

目的分析导致乳腺癌患者术后感染的危险因素,为降低乳腺癌术后感染率提供参考依据。方法选取医院2011年10月-2012年10月乳腺癌手术患者108例,收集其一般资料以及手术相关因素,并与乳腺癌患者术后感染的相关性进行单因素分析;采用SPSS 12.0软件进行分析,其相关性采用χ2检验。结果年龄、体质量指数、文化程度、进行手术的季节、手术持续时间和是否合并基础疾病等均与患者术后感染差异无统计学意义,手术方式和引流量的区别对于患者是否术后感染差异无统计学意义,化疗的患者术后感染率显著高于未接受化疗的患者(χ2=7.224,P=0.007),骨髓抑制的患者术后感染率显著高于未骨髓抑制的患者(χ2=11.542,P=0.001),引流时间与输血方式也对术后感染率差异有统计学意义(χ2=12.598、P<0.01,χ2=11.331、P<0.01)。结论临床对于化疗、骨髓抑制、引流天数≥10d以及接受输血的乳腺癌患者应给予特别的注意,采取相应的措施减少不良反应,以降低术后感染的发生率。

OBJECTIVE To analyze the risk factors of infection after therapy in breast cancer patients so as to provide reference to reduce postoperative infection rates of breast cancer .METHODS Totally 108 cases of breast cancer surgery patients from Oct 2011 to Oct 2012 were selected ,general information was colleoted including age , BM I ,education level ,season of surgery ,duration of surgery and the presence of comorbidities ,and procedure-related factors ,including diabetes ,whether experienced adjuvant chemotherapy ,bone marrow suppression ,surgi-cal approach ,drainage ,drainage number of days ,and surgery ,blood transfusions ,and infection with breast canc-er patients were cualyzed by for single-factor analysis using SPSS 12 .0 software .to analysis .RESULTS Age , BMI ,education level ,the season for surgery ,duration of surgery and underlying diseases and postoperative infec-tion in patients had no significant correlation （P＆gt;0 .05） ,surgical approach and drainage difference whether the patient after surgery infection had no significant effect （P＆gt;0 .05） ,adjuvant chemotherapy in patients with postop-erative infection rate was significantly higher than patients who did not receive chemotherapy （χ2 = 7 .224 , P=0 .007） ,significantly higher than the incidence of postoperative infections in patients with bone marrow suppres-sion patients with bone marrow suppression （χ2 =11 .542 , P= 0 .001） ,drainage time and blood transfusion on postoperative infection rates had a significant impact （χ2 = 12 .598 , P＆lt; 0 .01 ;χ2 = 11 .331 , P＆lt; 0 .01 ） . CONCLUSION Clinical adjuvant chemotherapy for bone marrow suppression of drainage number of days ≥ 10 d and breast cancer patients receiving a blood transfusion should be given special attention and take nappropriate measures to reduce the adverse reactions so as to reduce the incidence of postoperative infections .