慢性肾功能衰竭血脂质紊乱与肾虚的关系

Relationship Between Lipid Metabolism Disorder and Deficiency of the Kidney in Chronic Renal Failure

为探讨慢性肾功能衰竭 (CRF)血脂质紊乱与肾虚的关系 ,将 57例 CRF分为肾虚明显组与肾虚不明显组 ,观察各组血脂质变化情况 ,并探讨其与痰、瘀兼证的关系 ,结果发现 :1 CRF患者 TG、apo B、apo B/ apo AI比值较正常对照组显著升高 (P<0 .0 1 ) ;2与对照组比较 ,CRF肾虚明显组与肾虚不明显组 TG均非常显著升高 (P<0 .0 1 ) ;肾虚明显组 TC、apo B、apo B/ apo AI比值均显著升高 (P<0 .0 5) ;肾虚明显组 TG、TC升高与肾虚不明显组有显著差异 (P<0 .0 5) ;3肾虚明显组痰湿兼证百分率较肾虚不明显组显著降低 (P<0 .0 5) ;4与对照组比较 ,痰、瘀不明显组脂质紊乱较痰、瘀明显组更趋严重。说明 CRF存在以 TG升高为主的脂质代谢异常 ,CRF脂质紊乱与肾虚关系密切。

To study on the relationship between lipid Metabolism disorder and deficiency of the kidney, accompanying symptoms of stagnation of phlegm and stasis in chronic renal failure(CRF),57 cases of CRF were divided into the two groups of conspicuous symptoms(A) and unconspicuous symptoms(B) of deficiency of the kidney,then the changes of lipid were observed,and compared with the normal group.The results showed that:①the values of TG,apoB,apoB/apoAI were more obviously increased in CRF group than that of the normal group(P<0.01).②in comparison with the normal group,the values of TG were obviously increased in the two groups of A and B(p<0.01);the values of TC,apoB/apoAI were obviously increased in A group (p<0.05),the increased values of TC、TG had significantly different between A and B were(p<0.05).③the percentage of accompanying symptoms of stagnation of phlegm in A group was more obviously decreased than that of B group (p<\{0.05);\}④the lipid disorder is more serious in the group of unconspicuous accompanying symptoms of stagnation of phlegm and stasis than that of the group of conspicuous accompanying symptoms,as compared with the normal group.It indicates that there is lipid metabolism disorder which is characterized by the increased TG,and which is closely related to the deficiency of the kidney in CRF.