急性心肌梗死患者入院时Killip分级与预后的关系

The relationship of Killip class on admission and prognosis of acute myocardial infarction

分析 413例急性心肌梗死患者入院时 Killip分级与临床预后的关系。结果 :Killip 级组和 Killip 级以上组性别及既往史无差异。但 Killip 级以上组较 级组年龄大 (6 7± 12 vs 6 0± 10 )、血清肌酸磷酸激酶 (CK)峰值高(34 6 9± 175 7vs 196 6± 1795 ,P<0 .0 1)、左室舒张未期容积大 (185± 16 vs 12 5± 47,P<0 .0 1) ,住院病死率高(4 7.9% vs 11.2 % ,P<0 .0 1)。多元 L ogistic回归分析发现 Killip分级与住院病死率 (回归系数为 2 .34 ,OR值 5 .43,P<0 .0 1)和左室舒张末期容积 (回归系数为 0 .6 75 ,OR值 4.5 1,P<0 .0 5 )相关 ,但与年龄、CK峰值相关不明显。结论 :急性心肌梗死入院时 Killip分级为住院病死率及左室扩张的独立相关因子。

Analyzing the relationship of Killip class on admission and prognosis in 413 cases of acute myocardial infarction. RESULTS:There are no difference between patients with Killip class 1 and Killip class >2 in sex and history. Comparing with patients with Killip class 1,patients with Killip class >2 were older (67±12 vs 60±10),had higher peak creatine kinase level (3469±1757 vs 1966±1795, P <0.01),had bigger left ventricular end diastolic volume (185±16 vs 125±47, P <0.01),and had higher in hospital martality (47.9% vs 11.2%, P <0.01). Multiple Logistic regression indicated that Killip classification correlated with in hospital martality and left ventricular end diastolic volume,but did not correlated with age and peak creatine kinase level. CONCLUSION:Killip class on admission in patients with acute myocardial infarction was the independent correlative factor of in hospital mortality and left ventricular end diastolic volume.