立体定向适形放疗加肝动脉灌注治疗肝癌

TREATMENT OF MODERATE AND ADVANCED HEPATOCELLULAR CARCINOMAS WITH STEREOCOPIC DIRECTIONAL SITUATED RADIOTHERAPY PLUS HEPATIC ARTERY EMBOLIZATION AND INFUSION

目的 :探讨立体定向适形放疗联合肝动脉灌注对中晚期肝癌的治疗效果。材料与方法 :自 1999年 6月～2 0 0 0年 5月 ,对 32例中晚期肝癌患者进行了立体定向适形放疗 ,联合顺铂、5 -氟脲嘧啶经股动脉穿刺插管肝动脉内灌注化疗。结果 :自治疗之日起 ,生存 1年以上者 10例 ,占 31.3% ,6～ 12个月 (14例 ) ,占 43 .8% ,5个月以下的 8例 ,占 2 5 % ,中位生存期 11个月。结论 :中晚期肝癌采用立体定向适形放疗联合肝动脉栓塞灌注 ,能够提高局部控制率。延长病人生存期 ,改善以往常规分割照射引起的毒副反应。充分显示出立体定向适形放疗联合肝动脉灌注对中晚期肝癌的良好效果。

Objective:To improve affects of stereocopic directional situated radiotherapy (SDSR) plus hepatic artery embolization and infusion in treating moderate and advanced hepatocelluler carcinomas (HCCs).Methods:32 patients were treated with SDSR plus transcatheter perfemoralis arteried infusion with DDP,5-Fu.Results:10 cases (31.3%) were suvivaling more than 1 year.from 6 to 12 months were 14 case(43.8%) and not extended 5 months were 8 cases (25%).The median survival time was 10 months.Conclusions:SDSR plus hepatis artery embolization and infusion used for moderate and advanced HCCs can increased the regional control rate,extend survival period,and reduce poisonousness of separated illuminate.Our present date showed the treatment of HCCs with SDSR plus hepatic artery embolization and infusion has an exact curative effect.