不同麻醉药物对神经外科患者生理指标的影响探讨

The discussion of the effect different narcotic drugs on physiological indicators for neurosurgical patients

目的探讨不同麻醉药物对神经外科患者生理指标的影响。方法回顾性分析我院神经外科90例患者的临床资料,根据麻醉药物不同分为芬太尼组和舒芬太尼组各45例,分别给予芬太尼和舒芬太尼进行麻醉,比较不同时段2组患者的HR、MAP以及心血管事件发生情况。结果舒芬太尼组患者在术前、气管插管、术后5min的HR、MAP均显著低于芬太尼组,P<0.05;舒芬太尼组患者心血管事件总发生率8.89%,显著低于芬太尼组患者的22.22%,P<0.05。结论舒芬太尼用于麻醉,生理指标更稳定,能够有效抑制气管插管时心血管和拔管时血压变化,且心血管疾病发生率低,临床使用更安全。

Objective To investigate the effect of different narcotic drugs on physiological indicators for neurosurgical pa-tients.Methods The clinical data of 90 patients in our hospital required neurosurgical anesthesia was taken for retrospective a-nalysis.According to the differences of physiological indicators ,they were divided into the fentanyl group and the sufentanil group ,and 45 patients in each group.They were given with fentanyl and sufentanil anesthesia.The postoperative physiological reactions and the occurrence of cardiovascular events of one group were compared.Results The recover spontaneously breath-ing time ,eye opening time and extubation time of the sufentanil group were significantly shorter than the control group , P〈0.05.The overall incidence of cardiovascular events in the sufentanil group was 8.89% ,significantly lower than the overall inci-dence of cardiovascular events in the fentanyl group with 22.22% ,P〈0.05.Conclusion The physiological indicator of sufen-tanil anesthesia in neurosurgical patients is more stable ,and the incidence of cardiovascular events is low ,and the clinical appli-cation is safe.