脑出血血肿扩大相关因素及预后分析

Analysis of the related factors and prognosis of enlargement of intracerebral hemorrhage

目的分析脑出血血肿扩大的相关因素,以及对预后的不良影响。方法回顾性分析我院160例脑出血患者的临床资料,并进行分析比较。结果 160例患者中存在血肿扩大者60例,非血肿扩大者100例;血肿扩大组6h内发生率较高为83.3%;2组患者间长期饮酒史、收缩压及舒张压水平、血肿部位、血肿形态、意识障碍与早期是否应用甘露醇比较差异有统计学意义(P<0.05);患者预后与其意识状况、首次血肿量、血肿扩大、收缩压水平及早期是否应用甘露醇有密切相关性(P<0.05)。结论脑出血后血肿扩大的发生率较大,高血压、长期饮酒及早期甘露醇的不合理应用是脑血肿扩大的危险因素,且血肿扩大可能是其预后不良的主要影响因素之一。

Objective To analyze the related factors for hematoma enlargement of intracerebral hemorrhage, as well as the adverse effects on prognosis. Methods The clinical data of 160 patients with cerebral hemorrhage were retrospectively analyzed and compared. Results There were 60 cases of hematoma enlargement and 100 cases of non-hematoma enlargement in all pa- tients with cerebral hemorrhage; the incidence in the group of hematoma enlargement was 83.3%, which was higher. There were statistically significant difference on long-term drinking history, level of systolic and diastolic blood pressure, area and form of hematoma, consciousness or unconsciousness as well as mannitol use or not in early stage between the two groups （P〈 0.05）. The prognosis of patients was closely related to consciousness, first hematoma volume, hematoma enlargement, systol- ic blood pressure level and mannitol use or not in early stage （P〈0.05）. Conclusion The incidence of hematoma enlargement after intracerehral hemorrhage is high, which is mainly caused by hypertension, long-term drinking and misuse of mannitol in early stage, and hematoma enlargement may be one of the main factors for poor prognosis.