摘要
心力衰竭(心衰)是一种常见的心血管系统疾病,而β肾上腺素能受体家族在心血管系统自身调节方面起到了至关重要的作用。新近发现的β3肾上腺素能受体(β3AR)因与β1AR、β2AR截然相反的负性肌力作用而受到较多关注。该文主要阐述β3AR在心室肌和心房肌中的作用,并特别概述了患有心衰的老年人心肌β3AR的变化及β3AR对老年性心衰的影响。
Heart failure（HF） is a common cardiovascular disease. β-adreneric eceptors are critical to the overall regulation of cardiac function. Unlike β1AR, 132 AR, the newly discovered β3 AR has been widely studied due to its negative inotropic action. Here is to highlight the effects of β3 AR on atrial and ventricular myocardium, especially serum changes of β3 AR and its effect in senile patients with heart failure.
出处
《医学综述》
2014年第7期1167-1169,共3页
Medical Recapitulate
基金
北京市自然科学基金(7122073)
首都医科大学基础-临床科研合作基金(14JL41)
首都医科大学"本科生科研创新"计划(xsky2012073)
