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慢乙肝肝硬化伴自发性腹膜炎患者外周血PCT和CRP水平、WBC计数变化及诊断价值 被引量:10

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摘要 目的观察慢性乙型肝炎(CHB)肝硬化伴自发性腹膜炎(SBP)患者血降钙素原(PCT)、CRP水平及WBC计数变化,分析三者诊断SBP的价值。方法收集CHB肝硬化伴SBP患者50例(SBP组)、不伴SBP患者50例(非SBP组),分别测定血中WBC计数及CRP、PCT水平,并绘制受试者工作特征(ROC)曲线,记录曲线下面积(AUC)、95%可信区间(95%CI)及特定诊断敏感性和特异性所对应的cut-off值。结果与非SBP组相比,SBP组血CRP、PCT水平及WBC计数均明显升高(P均<0.05);PCT与CRP的AUC均显著大于WBC(P均<0.05),cutoff值分别为0.415 ng/mL、17.15 mg/L。结论 CHB肝硬化伴SBP患者血WBC计数及CRP、PCT水平显著升高,后两者诊断SBP的价值更高。
出处 《山东医药》 CAS 2014年第15期49-50,共2页 Shandong Medical Journal
基金 烟台市科技发展计划项目(2010152)
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