补肾活血祛痰方治疗肥胖型与非肥胖型多囊卵巢综合征的疗效研究

Study on Clinical Effects of Kidney-invigorating Blood-activating Phlegm-eliminating Prescription in Treating Polycystic Ovary Syndrome of Obesity Type and Non-obesity Type

目的:观察补肾活血祛痰方治疗肥胖型与非肥胖型多囊卵巢综合征(Polycystic ovary syndrome,PCOS)的临床疗效。方法:依据PCOS标准,收集肥胖型PCOS患者与非肥胖型PCOS患者共52例,采用补肾活血祛痰方进行治疗。观察患者治疗前后月经周期、排卵、肥胖、多毛、黑棘皮症、痤疮等临床症状及血睾酮(Testosterone,T)、胰岛素(Insulin,INS)、黄体生成激素(Luteoinizing hormone,LH)、卵泡刺激素(Follicle stimulating hormone,FSH)等变化情况。结果:补肾活血祛痰方既能改善患者肥胖、多毛、黑棘皮症、痤疮等临床症状(P<0.05),又能降低患者的血T、INS和LH水平(P<0.05)。结论:补肾活血祛痰方可降低PCOS患者的血T水平,改善患者胰岛素抵抗状态,对PCOS有较好的治疗效果。

Objective：To observe clinical effects of kidney-invigorating blood-activating phlegm-eliminating prescription in treating polycystic ovary syndrome （PCOS） of obesity type and non-obesity type. Methods：According to the standard of PCOS, 52 cases were collected and treated with kidney-invigorating blood-activating phlegm-eliminating prescription. Changes of testosterone （T）, insulin （INS）, luteinizing hormone （LH）, follicle stimulating hormone （FSH） and clinical symptoms such as menstrual cycle, ovulation, obesity, hairiness, acanthosis nigricans, acne and others of both groups were observed before and after treating. Results： Kidney-invigorating blood-activating phlegm-eliminating prescription could not only improve clinical symptoms including obesity, hairiness, acanthosis nigricans and acnes of the patients, but also decrease the levels of blood T, INS and LH （P〈0.05）. Conclusion：Kidney-invigorating blood-activating phlegm-eliminating prescription could decrease the level of blood T, improve insulin resistance of the patients and it is effective in treating PCOS.