107例非传染性输血并发症的原因分析及对策

Analysis of the causes and countermeasures of non-infectious complications of blood transfusion in 107 cases

目的调查分析107例非传染性输血并发症产生的原因，探讨有效降低非传染性输血并发症的技术措施。方法对2008年7月-2012年12月武威市人民医院，接受输血治疗的13767名患者，发生非传染性输血并发症的107例患者的资料进行回顾性调查分析，并作统计学比较。结果107例非传染性输血并发症中，男、女非传染性输血并发症的发生率无统计学差异（P〉0．05），有输血史、妊娠史患者的非传染性输血并发症的发生率高于无输血史、妊娠史的患者（P〈0．05）；3种血液成分的比较中，血浆引起的非传染性输血并发症明显高于红细胞和机采血小板（P〈0．05），血浆以过敏反应为主，红细胞和机采血小板分别以发热反应和血小板输注无效为主。结论提高科学合理用血水平及输血新技术、新方法（非传染性输血反应3步分析诊断法）的应用，可有效降低非传染性输血并发症的发生。

Objective To investigate the causes of non-infectious transfusion complications in 107 cases ,discuss techni-cal measures to reduce non-infectious transfusion complications. Methods From July 2008 to December 2012,Wuwei City People＇s Hospital performed 13 767 cases of transfusion therapy in 107patients with non-infectious transfusion complications which were retrospectively analyzed with statistical comparisons. Results There was no significant difference （ P 〉 0. 05 ） in incidence of 107 non-infectious blood transfusion complications cases between males and females,however, higher incidence in patients with history of blood transfusion and pregnancy in all non-infectious complications of blood transfusion with statisti-cal significance （ P 〈 0. 05 ） ; compared with three kinds of blood components, the non-infectious complication incidence of blood transfusion is significantly higher in plasma apheresis than in either platelets or red blood cells （ P 〈 0. 05 ）. The main reactions are allergic reaction plasma transfusion, fever reaction in red blood ceils and FFR in platelets. Conclusion Scien-tific and rational use of blood and application of new technologies or new Methods in blood transfusion （ non-infectious trans-fusion reactions 3 step analysis diagnostics） can effectively reduce the incidence of non-comnmnicable transfusion complica-tions.