2型糖尿病患者血浆sTM变化的研究

Study on plasma sTM change in Type 2diabetes mellitus patients

目的探讨血浆sTM在2型糖尿病患者中的变化特点。方法采用双抗夹心ELISA法检测50例正常人(对照组)、125例糖尿病无并发症、70例糖尿病并发症患者血浆sTM。结果糖尿病无并发症组和糖尿病并发症组患者,血浆sTM水平高于正常对照组(P<0.05),且糖尿病并发症组显著高于糖尿病无并发症组(P<0.01)。结论血浆sTM含量的增加在糖尿病及其并发症的发生发展中发挥了重要作用,可能是2型糖尿病并发症的早期预测指标。

Objective To investigate the changes in the characteristics the plasma sTM in type 2 diabetes mellitus. Methods we adopt double anti sandwich ELISA method to detect the 50 cases of normal person （control group）and 125 cases of diabetes without complications, 70 cases of patients with diabetes complications plasma sTM. Results The diabetes without complications and complications of diabetes patients, the plasma sTM levels were higher than those in normal control group （P〈0.05）, and complications of diabetes group were significantly higher than those in non-complication group （ P〈0.01 ）. Conclusion the plasma sTM content increases in diabetes and its complications played an important role in the development, may be a complication of type 2 diabetes early predictive indexes.