重庆市某机关单位体检人群动脉粥样硬化患病率及相关性分析

Revalence rate of atherosclerosis in health check-up subjects of one administration unit in Chongqing and its correlation analysis

目的:通过检测健康体检人群心-踝血管指数(cardio-ankle vascular index,CAVI),分析动脉粥样硬化(atherosclerosis,AS)发生的危险因素。方法:纳入2012年在重庆医科大学附属第一医院健康体检的重庆市某机关单位875人,测量其CAVI、身高、体质量、血压及空腹状态下的血脂和血糖等项目;根据CAVI结果分为AS组102人和非AS组701人,对不同组别的不同人群行单因素及多因素logistic回归分析。结果:AS组的年龄、男性比例、收缩压、舒张压和空腹血糖等高于非AS组(P<0.05);年龄、性别、体质指数(body mass index,BMI)、收缩压、甘油三酯是AS的独立危险因素,其中年龄对AS的影响作用最大(OR=4.375)。结论:AS的发生与多因素综合作用有关,应加强高危人群的定期体检,通过控制血压、血糖和血脂等危险因素,降低AS的发生率。

Objective ：To analyze the occurrence of atherosclerosis（AS） and its risk factors by examining the cardio-ankle vascular index（CAVI） in health examination group,so as to provide evidences for the prevention and treatment of AS. Methods：We examine a group of 875 persons from an institution of Chongqing underwent health examination in health examination center of the First Affiliated Hospital of Chongqing Medical University. The general indexes in the examination included CAVI, height, weight, blood pressure, fasting blood lipids and blood glucose,etc. Then according to the results from arteriosclerosis detector,the samples were divided into atherosclerotic positive group including 102 persons and non atherosclerosis group including 701 persons. Univariate and multivariate logistic regression analysis were conducted for different groups. Results：Male proportion, age, systolic blood pressure, diastolic blood pressure and fasting blood glucose of atherosclerotic positive group were significantly higher than those of non atherosclerosis group （P〈0.05）. Age, sex, body mass index, systolic blood pressure and triglyceride were independent risk factors of AS, among which age was the most significant factor（OR=4.375）. Conclusions ：The occurrence of AS is related with multiple factors. Therefore, a periodic health examination for high risk group combined with controlling of blood pressure, blood glucose and blood lipids is necessary to re- duce the occurrence of AS.