原发性高血压合并靶器官损害相关因素研究

A study of correlative factors in essential hypertension associated with target organ damage

[目的 ] 研究原发性高血压患者合并靶器官损害的相关因素。 [方法 ] 2 42例原发性高血压患者分为靶器官损害组 (TOD组 )和无靶器官损害组 (NTOD组 )。对两组 2 4h动态血压监测 (ABPM )结果进行分析。 [结果 ] TOD组夜间血压下降率SBP和DBP分别为 4.0 %和 5 .6% ,明显低于NTOD组的 10 .9%和 11.2 % (P <0 .0 1) ,TOD组昼夜节律减弱或消失者为 69.7% ,明显高于NTOD组的 3 9.2 % (P <0 .0 1) ,夜间SBP负荷值增高TOD组 68.3 %高于NTOD组 5 3 .6% (P <0 .0 5 )。 [结论 ] 原发性高血压合并靶器官损害和 2

[Objective] To study the correlative factors in essential hypertension associated with target organ damage. [Methods] 242 cases of essential hypertension were divided into target organ damage (TOD) group and non target organ damage (NTOD) group. The results of 24 hours ambulatory blood pressure monitoring were analyzed. [Results] The night systolic and diastolic blood pressure decrease rate in TOD group were 4% and 5.6%, obviously lower than that in NTOD group 10.9% and 11.2%(P<0.01).The day-night rhythm decrease or disappear value in TOD group were 69.7% , obviously higher than that in NTOD group 39.2%(P<0.01). Night systolic blood pressure load increase in TOD group was 68.3% higher than that in NTOD group 53.6%(P<0.05). [Conclusions] The TOD in essential hypertension has good correlation with 24 hours ambulatory blood pressure monitoring results.