摘要
目的考察注射用头孢拉定和缩宫素注射液配伍的稳定性。方法在20℃下8 h内考察注射用头孢拉定和缩宫素注射液配伍后,其混合溶液的外观及不溶性微粒变化,并用高效液相色谱法测定药物的含量。结果注射用头孢拉定和缩宫素注射液配伍后,8 h内药物的含量、混合溶液的外观及不溶性微粒均无明显变化。结论注射用头孢拉定和缩宫素注射液不存在理化性的配伍禁忌。
Objective To study the compatible stability of cefradine for injection when it was combined with oxytocin injection. Methods The change of appearance and indissoluble particle in the mixture within 8 h at 20 ℃ were observed after cefradine for injection being combined with oxytocin injection. The contents of drugs were determined by HPLC. Results No significant change was found in content, appearance and indissoluble pa：icle in 8 h after cefradine injection being combined with oxytocin injection. Conclusion There is no physical and chemical compatibility taboo when cefradine for injection is combined with oxytocin injection.
出处
《今日药学》
CAS
2014年第3期213-215,共3页
Pharmacy Today
