进口与国产恩替卡韦治疗慢性乙型肝炎的成本及效果分析

Cost-effectiveness Analysis on Lmport and Domestic Entecavir for Therapy of Chronic Hepatitis b

目的:比较进口与国产恩替卡韦治疗慢性乙型肝炎的成本-效果。方法:选取我院收治的50例慢性乙型肝炎患者,随机分为研究1组与研究2组各25例。研究1组给予国产恩替卡韦分散片进行治疗;研究2组采用进口恩替卡韦片进行治疗。结果:研究1组与研究2组的总有效率分别为64.0%、68.0%;治疗成本分别为2784元、5712元;成本-效果比较比(C/E)分别为43.5、84。结论:国产与进口恩替卡韦在治疗慢性乙型肝炎方面均具有显著疗效,且国产恩替卡韦治疗成本较低,具有临床推广应用价值。

Objective：To compare cost-effectiveness import and domestic entecavir for therapy of chro-nic hepatitis B .Method：50 cases of chronic hepatitis B patients were selected ,they were randomly divided into study 1 group and study 2 group, each group with 25 cases.Study 1 group were given domestic entecavir dispersible tablet;Study 2 group were given imported entecavir tablets .Result： The total effective rate of Study 1 group and Study 2 group was 64.0%and 68.0%; the treatment cost was respectively 2788.8 yuan and 5712 yuan;cost-effectiveness ratio （ C/E） was 43.6 and 84.Conclusion：Domestic and imported ente-cavir have significant effect on chronic hepatitis B , and domestic entercavir lower cost in treatment , It＆#39;s wor-thy of clinical application .