恶性肿瘤并发血栓形成的危险因素及治疗

Concurrent Malignancy Thrombosis Risk Factors and Treatment

目的:探讨恶性肿瘤并发血栓患者的临床危险因素和疾病特点。方法:选取2009年11月至2011年6月43例确诊的恶性肿瘤并发血栓性疾病患者列入实验组,取同期诊治的43例恶性肿瘤且未发生血栓并发症患者43例列入对照组,对比分析并发血栓患者的临床危险因素、实验室指标、治疗和预后。结果:恶性肿瘤并发血栓性疾病复发率高,患者生存率低;该病高发于肿瘤确诊后2个月内,治疗前红细胞计数、血浆凝血酶原时间、D-二聚体等实验室指标明显变化,恶性肿瘤并发血栓的危险因素包括地塞米松用药、手术刺激、输血、化疗、感染等。结论:及早发现,正确诊断,积极预防、治疗血栓性疾病有助于恶性肿瘤患者的临床疗效。

Objective：To investigate the clinical risk factors and characteristics of patients with malig-nant tumor complicated with thrombosis .Method： From Nov.2009 to Jun.2011, 43 cases of malignant tumor patients with thrombotic diseases included in the experimental group , 43 cases of malignant tumor di-agnosis and treatment and take over the same period without the occurrence of thrombotic complications in 43 patients as control group , analysis , treatment and prognosis of clinical risk factors of thrombosis in patients with laboratory index , contrast .Result： Malignant tumor patients with thrombotic disease with high recur-rence rate, survival rate was low;the disease incidence in cancer diagnosed after 2 months before treatment , red blood cell count , prothrombin time , D-two dimer and other laboratory indicators of change , risk factors of malignant tumor complicated with thrombosis including dexamethasone administration , operation stimula-tion, blood transfusion, chemotherapy infection, etc.Conclusion： The clinical should take early discovery for correct diagnosis , which can improve the total effective rate by energetic prevention and treatment .