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转化生长因子β1与心肌纤维化的研究进展 被引量:6

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摘要 转化生长因子是迄今为止已知的最为有效且功能较多的多肽类物质之一。它有多个亚型,其中转化生长因子β1(TGF-β1)作为心血管系统是最重要的异构体,参与了对基质金属蛋白酶系统、肾素-血管紧张素-醛固酮系统以及炎症和免疫系统的调节,促进心肌纤维化。而心肌纤维化是多种心脏病的共同病理基础,现就 TGF-β1与心肌纤维化的关系进行综述。
出处 《医学理论与实践》 2014年第8期1007-1008,990,共3页 The Journal of Medical Theory and Practice
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