皮硝外敷对老年腹部手术患者术后早期炎性肠梗阻的作用

The effect of Natrii sulfas external applying for aged patients with early postoperative inflammatory bowel obstruction after abdominal surgery

目的观察皮硝外敷对老年腹部手术患者术后早期炎性肠梗阻的作用。方法将35例术后早期炎性肠梗阻患者随机分为观察组19例和对照组16例,除观察组加用皮硝外敷外,2组患者的治疗方法相同。分别观察2组患者治疗前后腹胀消失时间、肛门排气时间、血清肌酸磷酸激酶水平、血清C反应蛋白水平、血清IL-6水平和TNF-α水平等的变化,同时,观察两组患者治疗前后的感染发生率和术后住院时间。结果与对照组比较,观察组患者术后腹痛、腹胀均明显缓解(P<0.05),肛门排气时间缩短(P<0.05)。观察组术后5d血清CPK值水平较对照组明显降低(P<0.05),术后3d、7d血清CRP水平也分别降于对照组(P<0.05),并且,其血清IL-6、TNF-α水平下降速度也明显快于对照组(P<0.05);术后感染发生率较对照组明显降低(P<0.05),术后住院时间明显缩短(P<0.05)。结论采用皮硝外敷可有效地缓解老年术后早期炎性肠梗阻患者的临床症状,促进肠功能恢复和改善患者临床转归。

Objective To investigate the effect of Natrii sulfas external applying for aged patients with early postoperative In-flammatory small bowel obstruction （EPISBO） after abdominal surgery. Methods Thirty-five cases of aged patients with EPISBO were randomly divided into treatment group （n=19） and control groups（n=16）,and the same treatment was given in two groups ex-cept that the treatment group were applied externally with Natrii sulfas. The disappearing time of abdominal distention ,the time of anus exhaust,the levels of serum creatine phosphokinase （CPK）,the levels of serum C-reactive protein （CRP）,the levels of serum IL-6,the levels of serum TNF-alphe,the incidence of postoperative infection and the time of hospital stay of the patients with EPISBO in two groups before and after treatment were observed and compared respectively. Results Compared with the control group,the clinical symptoms such as abdominal pain and distention in the treatment group were significantly eased （P〈0.05）,the time of anus exhaust was shortened （P〈0.05）. the levels of CPK in the treatment group after surgery 5d was lower than the control group,and the levels of CRP and serum IL-6,TNF-α of the treatment groups after surgery 3d,7d were lower than the control group respectively （P〈0.05）,and the incidence of postoperative infection was decreased significantly （P〈0.05）,and the time of hospital stay was shorten （P〈0.05）. Conclusion Natrii sulfas external applying can effectively eased the clinical symptoms of the aged patients with EPISBO,promote the recovery of intestinal function and improve the clinical outcome.