摘要肝素诱导的血小板减少症（HIT ）是抗肝素／血小板因子4复合物抗体介导的自身免疫性疾病，是肝素引起的少见而严重的并发症，发生率约0.5％～5％，发生 HIT 后患者的截肢率和死亡率可高达20％左右［1-3］。2008年1月～2013年1月本院体外循环下心脏直视术后并发HIT患者15例，经过治疗和护理，除1例死于多脏器衰竭外，其余均康复出院。
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