采用低压抗重力虹吸可调压分流管治疗正常颅压脑积水的疗效观察

Treatment of idiopathic normal pressure hydrocephalus with adjustable and gravitational siphon at low-pressure

目的探讨低压抗重力虹吸可调压分流管治疗特发性正常颅压脑积水(INPH)患者的疗效。方法回顾性分析22例采用低压抗重力虹吸可调压分流管和19例采用中压可调压管治疗的INPH患者的临床资料,42例患者中男23例,女19例;平均年龄(71.0±5.6)岁。结果 22例低压抗重力虹吸可调压分流管组在远期随访中共有18例有效,有效率81.8%;19例中压可调压分流管组在远期随访中10例有效,有效率52.6%;2组疗效差异有统计学意义(P<0.05)。结论采用低压抗重力虹吸可调压分流管治疗特发性正常颅压脑积水可取得良好的疗效,同时也不增加过度引流的风险。

Objective To investigate the curative effect of adjustable and gravitational siphon at low-pressure on idiopathic normal pressure hydrocephalus （INPH） patients. Methods Respective analysis was made by using the clinical medical data of 22 IN- PH patients treated with low-pressure gravitational siphon and 19 INPH patients treated with adjustable medium-pressure gravitatal si- phon. Of all the 41 cases, 22 were male and 19 were female, with an average age of（ 71.0 ± 5.6 ） years old. Results In the long-term follow-up, of the 22 patients treated with adjustable and gravitational siphon at low pressure, 18 well responded to the treatment, with an effective rate of （81.8%）, and of the 19 patients treated with adjustable shunt at medium pressure, 10 responded to the treatment, with an effective rate of （52.6%） . And statistical significance could be noted, when comparisons were made between the groups（P 〈 0.05 ）. Conclusion Adjustable and gravitational siphon at low pressure could produce good effect on INPH, and at the same time could reduce risks associated with excessive drainage.