原发性肝癌手术治疗与肝动脉化疗栓塞疗效比较的Meta分析

META ANALYSIS OF COMPARATIVE STUDY OF TREATMENT OF HEPATOCELLULAR CARCINOMA WITH HEPATIC RESECTION AND TRANSCATHETER ARTERIAL CHEMOEMBOLIZATION

目的采用Meta分析法 ,对国内、外有关原发性肝癌 (hepatocellularcarcinoma ,HCC)的手术治疗与肝动脉化疗拴塞 (transcatheterarteralchemoembolization ,TAC)疗效比较的单项研究进行综合评价和定量分析。方法Meta分析步骤包括收集相关文献、确定纳入和排除Meta分析文献标准、相关文献的质量评定、选择统计学处理方法进行资料综合。结果HCC手术与TAE疗效对比研究的 1年、3年生存率合并率差 95 %可信区间分别为- 0 .0 8941～ 0 .1177和 - 0 .1380～ 0 .0 6 72 ,均包括“0”。结论HCC手术与TAE的长期生存率无统计学差异 (P >0 .0 5 )。

ObjectiveMeta analysis method was used to analyze survival rates hepatocellular carcinoma(HCC)of patients treated with operation and transcatheter arterial chemoembolization(TAC) reported in different periodicals to evaluate quantitativelly the two treatment procedures.MethodsThe Meta analysis was done as follows: collection of relative literatures,literatures selection according to our criterion, abstraction of analysis items from the selected reports, and selection of statistical methods.ResultsThe results showed that the 95 % confidence interval of integrated RD of survival rated for 1 or 3 years on the treatment effect between operation and TAC are - 0.0841 ～ 0.1177 and - 0.1380 ～ 0.0672 respectively,all of which included zero.ConclusionThere was no difference in the survival rates between HCC patients treated with operation and TAC.