摘要
目的:建立抗骨增止疼片薄膜包衣的处方及工艺。方法:欧巴代作成膜材料,对抗骨增止疼片进行薄膜包衣。结果:包衣后的片剂外观色泽均匀,硬度、片重差异、崩解时限等指标均符合《中华人民共和国药典》2010年版的要求,包衣后药物的引湿性有明显的改善。结论:采用欧巴代进行包衣,有效地降低了药物的吸湿性,该工艺操作简单可行,适合工业化生产。
Objective：To prepare the Kangguzengzhiteng film-coating Tablets. Methods：Opadry is selected to be the film coating material in Kangguzengzhiteng Tablets. Results：The appearance, hardness, weight difference and disintegration time of the tablets were in line with the relevant requirements of pharmacopoeia of the People＇s Republic of China（2010 edition）. The hygroscopicity of the tablet was significantly decreased after film-coating. Conclusion ： The bygroscopicity of Kangguzengzbiteng film-coating Tablets is significantly decreased after film-coating with Opadry.
出处
《亚太传统医药》
2014年第8期21-22,共2页
Asia-Pacific Traditional Medicine
关键词
抗骨增止疼片
欧巴代
薄膜包衣
Kangguzengzhiteng Tablets
Opadry
Film-coating
