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一氧化氮与缺氧缺血性脑损伤的神经元凋亡 被引量:7

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摘要 近年来研究发现 ,神经元凋亡是缺氧缺血性脑损伤过程中神经元死亡的一种重要形式 ,而一氧化氮作为迄今发现的第一个气体信息分子在缺氧缺血性脑损伤中起重要作用。文章综述了脑缺氧缺血损伤后神经元凋亡 ,一氧化氮的变化及两者的关系。
作者 姚瑜 俞惠民
出处 《国外医学(脑血管疾病分册)》 2001年第1期8-11,共4页 Foreign Medical Sciences Cerebrovascular Diseases
基金 浙江省自然科学基金资助项目!(NO .3 9842 8)
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  • 1Dell'Anna E, Chen Y, Engidawork E, et al. Delayed neuronal death following perinatal asphyxia in rat. Exp Brain Res. 1997,115 ( 1 ): 105-115.
  • 2Edwards AD, Yue X, Cox P, et al. Apoptosis in the brains of infants suffering intrauterine cerebral injury. Pediatr Res, 1997, 42:684-689.
  • 3Iadecola C, Zhang F, Xu S, et al. Inducible nitric oxide synthase gene expression in brain following cerebral ischemia. J Cereb Blood Flow Metab, 1995,15: 378-384.
  • 4Tamatani M, Ogawa S, Niitsu Y, et al. Involvement of Bcl-2 family and caspase-3-1ike protease in NO-mediated neuronal apoptosis. J Neurochem, 1998,71(4): 1588-1596.
  • 5Okuma Y, Uehara T, Miyazaki H, et al. The involvement of cytokines,chemokines and inducible nitric oxide synthase (iNOS) induced by a transient ischemia in neuronal survival/death in rat brain. Nippon Yakurigaku Zasshi, 1998,111 ( 1 ): 37-44.
  • 6Keller JN, Kindy MS, Holtsberg FW, et al. Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production. lipid peroxidation.and mitochondrial dysfunction. J Neurosci, 1998. 18(2): 687-697.
  • 7Vincent AM, TenBroeke M, Maiese K. Neuronal intracellular pH directly mediates nitric oxide-induced programmed cell death. J Neurobiol,1999,40(2): 171-184.
  • 8Loidl CF, De-Vente J, van Ittersum MM, et al. Hypothermia during or after severe perinatal asphyxia prevents increase in cyclic GMP-related nitric oxide levels in the newborn rat striatum. Brain Res, 1998, 791 ( 1-2) :303-307.
  • 9Li Y, Chopp M, Jiang N, et al. Induction of DNA fragmentation after
  • 10to 120 minutes of focal cerebral ischemia in rats. Stroke, 1995, 26(7): 1252-1258.10.Stoll G, Jander S, Schroeter M. Inflanumation and glial responses in ischemic brain lesions. Prog Neurobiol, 1998,56(2) :149-171.

同被引文献55

  • 1邓奕辉,崔莲珠,喻嵘,李定祥,陈大舜.降糖通脉方治疗糖尿病合并脑梗死32例临床观察[J].湖南中医学院学报,2004,24(5):40-42. 被引量:21
  • 2茅惠明.血清中硝酸盐的镀铜镉还原测定法[J].临床检验杂志,1995,13(1):6-8. 被引量:47
  • 3许宏岳,李爱红,汪晓,胡明昌.比色法测定血清亚硝酸盐和硝酸盐及初步临床应用[J].临床检验杂志,1996,14(1):28-28. 被引量:57
  • 4张天锡,孙青芳,田恒力,赵卫国,董克家.局灶脑缺血后早、晚期一氧化氮合成酶的活性变化[J].临床神经科学,1996,4(4):187-189. 被引量:2
  • 5泉x雄 烟隆克.NO合成酵素阻害剂が实验的脑梗塞の进展に及ぼす影响-MRI信号强度による经时的检讨[J].临床神病学,1999,39(1):169-169.
  • 6[4]Lennon SV, Martin SJ, Cotter TG. Dose-dependent induction of apoptosis in human tumor cell lines by widey diverging stimuli [J]. Cell Prolif, 1991, 24:203
  • 7[5]Clarke AR, Purdie CA, Harrison DJ, et al. Thymocyte apoptosis induced by P53- dependent and independent pathway[J]. Nature, 1993, 362 (6423): 849
  • 8[6]Li Y, Chopp M, Jing N, et al. In situ delection of DNA fragmentation after focal cerebral ischemia in mice [J]. Brain Res Mol Brain Res, 1995, 28 (1): 164
  • 9[11]Greenland LT, Deckwerth TL, Johnson EM. Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death [J]. Neurou, 1995,14: 303
  • 10[12]Johnson EM, Greenlund LT, Akins PT, et al. Neuronal apoptosis current understanding of molecular mechanisms And potential role in ischemic brain injury [J]. J Neurotrauma,1995, 12: 843.

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