680例女性患者泌尿生殖系统支原体感染及分布特征研究

Study on Mycoplasma infection and distribution characteristics in urogenital system of 680 female patients

目的：探讨女性患者泌尿生殖系统支原体感染及分布特征，为临床提供依据。方法：选取在湖北医药学院附属人民医院泌尿外科和妇科门诊就诊及住院的妇女680例，观察不同种类衣原体的分布情况、不同年龄人群的衣原体分布情况和药物敏感性。结果：解脲脲支原体（Uu）、人型支原体（Mh）和Uu＋Mh型感染率分别为46．76％、22．50％和30．74％，≤25岁、25～35岁、〉45岁和35—45岁衣原体感染率分别为6．03％、55．29％、28．53％和10．15％。强力霉素和交沙霉素药敏性最高，环丙沙星和氧氟沙星药敏性最低。结论：泌尿生殖道中支原体感染是以uu为主，婚后育龄妇女发生率较高，临床上应结合药敏结果合理选择抗生素进行治疗，最大限度降低耐药菌株的产生。

Objective： To explore Mycoplasma infection and distribution characteristics in urogenital system of female patients, and provide a basis for clinical treatment. Methods： A total of 680 female patients were selected from Department of Urology Surgery and De- partment of Gynecology in the hospital, the distributions of different types of Mycoplasma in different age groups and drug sensitivity were ob- served. Results： The infection rates of Ureaplasma urealyticum （Uu）, Mycoplasma hominis （Mh） and Uu ＋ Mh were 46.76%, 22. 50% and 30. 74% , respectively ; the infection rates of Mycoplasma in ≤ 25 - year - old group, 25 - 35 - year - old group, 〉 45 - year - old group and 35 -45 - year - old group were 6.03% , 55.29% , 28.53% and 10. 15% , respectively; the drug sensitivities of doxycycline and josamycin were the highest, while the drug sensitivities of ciprofloxaein and ofloxacin were the lowest. Conclusion： Uu is the main type of Mycoplasma infection in urogenital system, the incidence rate of Mycoplasma infection is high in married women of childbearing age, antibiot- ics should be applied reasonably according to drug sensitivity test to minimize the emergence of resistance strains.