青岛市中老年人糖尿病及糖调节受损的流行现状分析

Analysis on the Prevalence of Diabetes and Impaired Glucose Regulation Among Middle-aged and Elderly Residents,Qingdao City

目的了解青岛市30岁以上居民糖尿病及糖调节受损的患病现状并分析影响因素,为以后青岛市糖尿病和糖尿病前期的防治工作提供依据。方法采用多阶段分层随机抽样方法,共调查6 069人,进行问卷调查、体格检查和实验室检查,指尖血糖值<7.00mmol/L者做口服糖耐量(OGTT)试验。采用SPSS 17.0统计软件进行分析,做单因素和多因素非条件Logistic回归,分别对糖尿病和糖调节受损的影响因素进行分析。结果 5 683名调查对象中,糖尿病(DM)患病率为15.71%,糖调节受损(IGR)的患病率为29.72%,其中单纯空腹血糖受损(IFG)、单纯糖耐量减低(IGT)和空腹血糖受损合并糖耐量低减(IFG/IGT)的患病率分别为10.29%、13.25%和6.18%。IGT、IFG/IGT、DM的患病率随年龄的增加呈现上升趋势(P<0.01)。多因素Logistic回归显示年龄、DM家族史、脑中风史、高血压、向心性肥胖、高TC血症、高TG血症是DM的危险因素;年龄、饮酒、高血压、向心性肥胖、高尿酸血症是IGR的危险因素。结论青岛市30岁以上居民DM及IGR流行状况严重,年龄、高血压、向心性肥胖是青岛市中老年人IGR和DM的共同危险因素。

Objective To understand the prevalence and risk factors of diabetes mellitus （DM） and impaired glucose reg- ulation （IGR） among the residents above 30-year old in Qingdao city,so as to provide the basis for prevention and control of diabetes and pre-diabetes. Methods Cluster stratifiedMultistage stratified cluster random sampling method was con- ducted among 6 069 residents, to perform questionnaire survey, physical examination and lab testing. Oral glucose tolerance test （OGTT） was performed among subjects with fasting plasma glucose （FPG） below 7.00 mmol/L. Statistical analysis of invariant,Logistic equation were used to identify risk factors of DM and IGR. Results The prevalence of DM and IGR was 15.71~~ and 29.72~/00 in 5 683 subjects, including the prevalence of IFG, IGT and IFG/IGT was 10.29~/oo, 13.25 ~ and 6.18 %. The prevalence of IGT,IFG/IGT and DM increased with age（ P d0. 001）. Age,DM family history, cerebral apoplexy,hypertension, central obesity, hypertriglyceridemia, and hypercholesterinemia were the risk factors for IDM;and age,drinking,central obesity,hypertension,hyperuricemia were the risk factors for IGR. Conclusion DM and IGR are prevalent in the residents above 30-year old in Qingdao city. Age, hypertension, and central obesity are common risk factors for IGR and DM.