碱性氧化铝催化芳醛与丙二腈的Knoevenagel缩合反应

Knoevenagel Condensation of Aromatic Aldehydes with Malononitrile Catalyzed by Basic Alumina

无溶剂下,以碱性氧化铝为催化剂催化芳醛和丙二腈的Knoevenagel缩合反应,合成了一系列的芳基亚甲基丙二腈化合物.实验结果表明,该法具有操作和后处理简单、产率高、催化剂能够循环使用、对环境友好等优点,符合绿色化学的要求.

A series of arylmethylenemalononitrile compounds were synthesized by the Kno- evenagel condensation reactions of different aromatic aldehydes and malononitrile under solvent- free conditions catalyzed by basic alumina. The experimental results showed that the method pos- sessed the advantages of simple operation and work-up procedure, good yields, recyclable catalyst being and friendly to environment. It fulfills the requirement of green chemistry.