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抗中性粒细胞胞浆抗体检测对临床诊断的意义 被引量:2

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摘要 抗中性粒细胞胞浆抗体是一组以人中性粒细胞胞浆成分为靶抗原,与系统性血管炎密切相关的一类自身抗体。ANCA相关系统性血管炎(ANCA associated systemic vasculitis,AASV)是目前成人最常见的原发性血管炎。靶抗原主要为丝氨酸蛋白酶3(PR3)和髓过氧化物酶(MPO),在不同临床疾病阳性率分布不同,在累及器官的数量和程度上也有所不同。ANCA还可作为SLE病情监测的一种参考指标。ANCA的检测对临床诊断有着重要的指导意义,为了保证准确检测结果,建议实验室同时开展间接免疫荧光法(IIF)和酶联免疫吸附法(ELISA)两种方法学检测。
作者 胡勇
出处 《中国民族民间医药》 2014年第8期71-72,共2页 Chinese Journal of Ethnomedicine and Ethnopharmacy
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参考文献10

  • 1Falk RJ,Jennette JC.Thoughts about the classification of small vessel vasculit is[J].J Niphrol,2004,17(8):83.
  • 2Jayne D,Rasmussen N,Andrassy K,et al.Arandrmized trial of maintenance therapy for vasculitis associated with antineutrophril cytoplasnic autoantibodies.N Eng l J Med,2003,349(1):36-44.
  • 3彭兴.抗中性粒细胞胞浆抗体检测及其临床意义[J].中国实验诊断学,2005,9(1):147-148. 被引量:9
  • 4Geffriaud-Ricouard C,Noel LH,Chauveau D,et al.Clinical spectrum associated with ANCA of definied specificities in 98 selected patients[J].Clin Nephrol,1993,39:125-126.
  • 5Guillevin L,Visser H,Noel LH,et al.Antineutrophil cyto-plasm antibodies in systemic polyarteritis nodosa with and without hepatitis B virus infection and churg-strauss syndrome[J].J Rheumatol,1993,20:1345-1349.
  • 6Franssen CFM,Gans ROB,Kallenberg CGM,et al.Disease spectrum of patients with anti-neutrophil cytoplasmic autoanti-bodies:Distinct differences between patients with anti-pro-teinase 3 and anti-myeloperoxidase autoantibodies[J].J Intern Med,1998,244:209-216.
  • 7于峰,赵明辉,黄建萍,姚勇,邹万忠,章友康,王海燕.少年儿童抗中性粒细胞胞浆抗体相关原发性系统性血管炎的临床和病理特点[J].中华儿科杂志,2003,41(11):831-834. 被引量:19
  • 8Churg J,Bernstein J,Glassock RJ.Renal disease classification and atlas of glomerula-disease[M].Second edition.NewYork:Ikagu Shoin,1995,45-47.
  • 9龙必芳.ANCA检测在临床中的应用[J].中国实用医药,2009,4(31):69-70. 被引量:5
  • 10辛岗,赵明辉,章友康.抗中性粒细胞胞浆抗体3种检测方法的比较[J].北京医科大学学报,2000,32(1):82-83. 被引量:23

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同被引文献16

  • 1彭兴.抗中性粒细胞胞浆抗体检测及其临床意义[J].中国实验诊断学,2005,9(1):147-148. 被引量:9
  • 2陈惠萍.血管炎的分类及其诊断标准[J].肾脏病与透析肾移植杂志,1994,3(5):398-402. 被引量:3
  • 3林善锬,卢燕雯.抗中性粒细胞胞浆抗体检测在肾脏病诊治中的应用[J].中国实用内科杂志,1995,15(6):337-339. 被引量:9
  • 4Bombardier C,Gladman DD,Urowitz MB,et al. Derivation of the SLEDAI. A disease activity index for lupus patients. The Commit- tee on Prognosis Studies in SLE [J]. Arthritis Rheum,1992,35: 630-640.
  • 5Amett FC,Edworthy SM,Bloch DA,et al. The American Rheuma- tism Assoeaition 1987 revised criteria for the classification of rheumatoid arthritis[J]. Arthr Rhuem, 1988,31 : 315-324.
  • 6Sada KE, Yamamura M, Harigai M, et al. Classification and charac- teristics of Japanese patients with antineutrophil cytoplasmic anti- body-associatedvasculitis in a nationwide,prospective,inception cohort study[J]. Arthritis Res Ther,2014,16(2):R101.
  • 7Schuhe-Pelkum J,Radice A,Norman GL,et al. Novel Clinical and Diagnostic Aspects of Antineutrophil Cytoplasmic Antibodies [J]. J Immunol Res,2014,2014:185416.
  • 8Kudoh Y, Kuroda S ,Shimamoto K ,et al. Propylthiouracil-induced rapidly progressive glomerulonephritis associated with antineu- trophil cytoplasmic autoantibodies [J]. Clin Nephrol,1997,48(1): 41-3.
  • 9Schamp V,Verfaillie C,Bonroy C,et al. Propylthiouracil induced ANCA-assoeiated vasculitis in a 14-year-old girl [J]. Acta Clin Belg, 2015,70(2) : 127-129.
  • 10丁艳苓,朱红,姚婉贞,赵鸣武.抗中性粒细胞胞浆抗体阳性的弥漫性间质性肺病的临床分析[J].北京大学学报(医学版),2011,43(2):222-227. 被引量:5

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