期刊文献+

造血干细胞移植在骨髓增生异常综合征治疗中的作用和地位 被引量:1

下载PDF
导出
摘要 骨髓增生异常综合征(MDS)是起源于造血干细胞/前体细胞的克隆性疾病,主要发生于老年人,其诊断时的中位年龄为70~75岁,70~75岁间的发病率为40~60/100000/年。MDS在高加索人种中的发生率高于非高加索人种,在亚洲人种中发病年龄较小。MDS发病的危险因素包括前期放疗或化疗,尽管吸烟人群MDS发病率似乎高于不吸烟人群,但目前尚不能确定除前期放、化疗外其它发病相关的危险因素。
作者 冯茹 张晓辉
出处 《临床内科杂志》 CAS 2014年第3期155-158,共4页 Journal of Clinical Internal Medicine
  • 相关文献

参考文献19

  • 1De Roos A J,Deeg H J,Onstad L,et al.Incidence of myelodysplastic syndromes within a nonprofit healthcare system in western Washington state,2005-2006[J].Am J Hematol,2010,85(10):765-770.
  • 2Greenberg PL,Baer MR,Bennett JM,et al.Myelodysplastic syndromes:clinical practice guidelines in oncology[J].J Natl Compr Canc Netw,2006,4(1):58-77.
  • 3Fenaux P,Mufti G J,Hellstrom-Lindberg E,et al.Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes:a randomised,open-label,phase Ⅲ study[J].Lancet Onco1,2009,10 (3):223-232.
  • 4Prébet T,Gore SD,Esterni B,et al.Outcome of high-risk myelodysplastic syndrome after azacitidine treatment failure[J].J Clin Onco1,2011,29(24):3322-3327.
  • 5Kuendgen A,Strupp C,Aivado M,et al.Myelodysplastic syndromes in patients younger than age 50[J].J Clin Oncol,2006,24(34):5358-5365.
  • 6McClune BL,Weisdorf DJ,Pedersen TL,et al.Effect of age on outcome of reduced-intensity hematopoietic cell transplantation for older patients with acute myeloid leukemia in first complete remission or with myelodysplastic syndrome[J].J Clin Oncol,2010,28(11):1878-1887.
  • 7Itzykson R,Thepot S,Quesnel B,et al.Prognostic factors for response and overall survival in 282 patients with higher-risk myelodysplastic syndromes treated with azacitidine[J].Blood,2011,117 (2):403-411.
  • 8Oliansky DM,Antin JH,Bennett JM,et al.The role of cytotoxic therapy with hematopoietic stem cell transplantation in the therapy of myelodysplastic syndromes:an evidence-based review[J].Biol Blood Marrow Transplant,2009,15 (2):137-172.
  • 9Woodard P,Carpenter PA,Davies SM,et al.Unrelated donor bone marrow transplantation for myelodysplastic syndrome in children[J].Biol Blood Marrow Transplant,2011,17 (5):723-728.
  • 10Lee JH,Lee JH,Lim SN,et al.Allogeneic hematopoietic cell transplantion for myelodysplastic syndrome:prognostic significance of pre-transplant IPSS score and comorbidity[J].Bone Marrow Transplant,2010,45 (3):450-457.

同被引文献7

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部