甲泼尼龙冲击治疗急性脊髓炎的临床效果观察

Clinical Effect of Methylprednisolone Pulse Therapy Treating Acute Myelitis

目的探讨甲泼尼龙冲击治疗急性脊髓炎的临床效果。方法选取本院2012年3月—2013年5月收治的42例急性脊髓炎患者。随机将患者分为两组,观察组22例给予甲泼尼龙冲击治疗,对照组20例给予传统的地塞米松治疗。比较治疗后的疗效。结果治疗后观察组总有效率95.45%高于对照组65.00%,差异有统计学意义(P<0.05)。治疗后观察组排尿恢复时间及行走能力恢复时间均少于对照组,差异有统计学意义(P<0.05)。结论甲泼尼龙冲击治疗急性脊髓炎有明显的作用效果,能够让患者肌力早日恢复正常。

Objective To analyze the clinical effects of methylprednisolone pulse therapy treating acute myelitis. Methods 42 patients with acute myelitis in our hospital from March 2O12 to May 2O13 were randomly divided into two groups, the observation group（22 cases）was treated with methylprednisolone pulse therapy,the control group（22 cases）was treated with conventional dexamethasone. The changes of muscle force of patients after treatment were compared. Results After treat-ment,the total effective rate of observation group was 95. 45% ,which was higher than 65. OO% in control group,the difference was statistically significant（P ＆lt; O. O5）. After treatment,the micturition ability and walking ability of observation objiects were shorter than control group,the differences were statistically significant（P ＆lt; O. O5）. Conclusion The efficacy of methylpred-nisolone pulse on acute myelitis is significant,which can make the muscle force of patients return to normal as soon as possible.