幽门螺杆菌感染合并消化性溃疡的治疗分析

Diagnostic Analysis of Helicobacter Pylori Complicated with Peptic Ulcer Infection

目的探究幽门螺杆菌(Hp)感染合并消化性溃疡患者的有效治疗方法,为临床治疗提供依据。方法选择2009年1月—2012年11月本院门诊或病房收治的Hp感染合并消化性溃疡的患者86例,随机分成A、B组两组,各43例。A组给予奥美拉挫+阿莫西林+克拉霉素治疗,B组患者在A组治疗的基础上服用乳酸菌素片。比较两组患者临床效果及不良反应发生情况。结果 B组Hp根治有效率及临床治疗有效率均高于A组,不良反应发生率低于A组,差异有统计学意义(P<0.05)。结论益生菌联合三联疗法治疗消化性溃疡合并幽门螺杆菌感染疗效显著,不良反应少,值得临床推广应用。

Objective To explore the effective treatment for patients with Helicobacter pylori combined with peptic ul-cer infection and provide basis for clinical treatment. Methods 86 cases of Helicobacter pylori combined with peptic ulcer in-fection in this hospital from January 2OO9 to November 2O12,were randomly divided into group A and B,43 cases of each group. Group A was treated with omeprazole,amoxicillin and clarithromycin;Group B was treated with Lacidophilin tablets on the basis of group A. Clinical effect and adverse reactions occur of two groups were compared. Results Helicobacter pylori erad-ication rate and clinical treatment efficiency of group B were higher than those of group A,and the incidence of adverse reactions of group B was lower than that of group A,the difference were statistically significant（P 〈 O. O5）. Conclusion Probiotics combined with triple therapy treating Helicobacter pylori combined with peptic ulcer infection can improve the curative effect, and reduce the occurrence of adverse reactions,worthy of clinical popularization and application.