老年高血压患者高胰岛素血症和一氧化氮变化的临床意义

Significance of Clinical Hyperinsulinemia and NO in Old Patients with Hypertension

目的 研究老年高血压患者高胰岛素血症和 NO的关系。方法 测定 45例高血压患者 (2 3例伴高胰岛素血症 ,2 2例正常胰岛素血症 )和 2 0例正常人空腹血糖、血清胰岛素和 NO。结果 高血压 、 期血清胰岛素高于对照组 ,而 ISI低于对照组。 NO和血清胰岛素变化呈正相关。结论 对老年高血压治疗、降低胰岛素抵抗有重要意义。

Objective:To investigate the effects of hyperinsulinemia and NO in old patients with hypertension.Methods:Fast serum Glucose [FSG],fast serum insulin[INS]and NO were measured in 45 hypertension cases,[23 of them are with hyperinsulinemia and 22 with normal insulin level]and 20 healthy persons.Results:1 The level in the blood of hypertensives with hyperinsulinemia and obviously higher and lower than the without insulin resistance and The healthy group[P<0 01].2 Insulin and ISI of EH3,EH2 are obviously higher than the control group.[p<0 05]3 The NO of hypertensives and hyperinsulinemia are positive relation.Conclusion:The Results indicated that great majority elderly patients in EH group are associated with hyperinsulinmia insulin resistance and NO.Therefore in the process of tretment it is also important to reduce the insulin resistance.